CAJ | 학술논문

目的：调查长沙市体检人群血液同型半胱氨酸（Homocysteine，HCY）的含量，了解长沙市成人同型半胱氨酸（HCY）现状，为临床脑卒中研究及脑卒中防治提供数据参考。方法：收集2014年1月至2014年9月长沙市中心医院18岁以上体检者血液标本共1403例，采用酶循环法测定体检者血液同型半胱氨酸（HCY）值，并对检测结果进行统计分析。结果：同型半胱氨酸（HCY）男女均值分别为（17.54±7.95）umol/L、（12.10±4.20）umol/L，同一年龄组男性 HCY 均高于女性，男性不同年龄组的 HCY 差异无统计学意义，女性的 HCY 随着年龄加大而增加，男、女同型半胱氨酸（HCY）的异常检出率分别为54.98%、16.9%。结论：长沙市成人同型半胱氨酸（HCY）检测结果不容乐观，异常检出率男性高于女性同年龄组；女性的 HCY 值随着年龄加大而增加，建议定期做同型半胱氨酸（HCY）的检测，做到早发现早预防脑卒中。
목적：조사장사시체검인군혈액동형반광안산（Homocysteine，HCY）적함량，료해장사시성인동형반광안산（HCY）현상，위림상뇌졸중연구급뇌졸중방치제공수거삼고。방법：수집2014년1월지2014년9월장사시중심의원18세이상체검자혈액표본공1403례，채용매순배법측정체검자혈액동형반광안산（HCY）치，병대검측결과진행통계분석。결과：동형반광안산（HCY）남녀균치분별위（17.54±7.95）umol/L、（12.10±4.20）umol/L，동일년령조남성 HCY 균고우녀성，남성불동년령조적 HCY 차이무통계학의의，녀성적 HCY 수착년령가대이증가，남、녀동형반광안산（HCY）적이상검출솔분별위54.98%、16.9%。결론：장사시성인동형반광안산（HCY）검측결과불용악관，이상검출솔남성고우녀성동년령조；녀성적 HCY 치수착년령가대이증가，건의정기주동형반광안산（HCY）적검측，주도조발현조예방뇌졸중。
ObjectiveTo investigate the homocysteine(HCY) levels of healthy population in Changsha City, provide the reference for clinicalprevention and treatment for stroke in the local area. Methods 1403 adults’clinical data of Health ex-amination were collected from 2014 January to 2014 september in Changsha central hospital. The levels of Homocysteine were detected by circulating enzymatic method and results were conducted by statistical analysis. Results The mean HCY levels of men and women were (17.54+7.95) umol/L, (12.10+4.20) umol/L, respectively. the same age group of the levels of HCY in male were higher than that of in female, no significant differences in different age groups in male ,the levels of HCY in fe-male increased with age increasing, the detection rate of abnormal cysteine (HCY) of male and female is 54.98% and16.9%, respectively. Conclusions Adults’are not optimistic status in Changsha City, all in a word, the abnormal homocysteine (HCY) levels in male were higher than that of in women; women's HCY values increased with age increasing. Adults should be exam-ined the levels of homocysteine (HCY) to prevent and discovery stroke in early phase.