医学研究杂志
醫學研究雜誌
의학연구잡지
Journal of Medical Research
2015年
10期
97-99,113
,共4页
穆利英%李晶玮%李群%杨红廉
穆利英%李晶瑋%李群%楊紅廉
목리영%리정위%리군%양홍렴
颈动脉硬化%冠状动脉慢血流%回声跟踪技术%超敏C反应蛋白
頸動脈硬化%冠狀動脈慢血流%迴聲跟蹤技術%超敏C反應蛋白
경동맥경화%관상동맥만혈류%회성근종기술%초민C반응단백
Carotid arteriosclerosis%Coronary slow flow%Echo-tracking technology%High sensitivity-C reaction protein
目的 研究冠状动脉慢血流( coronary slow flow ,CSF)患者的颈动脉硬化情况. 方法 选取具有相似危险因素分层的CSF患者和冠状动脉血流正常(normal coronary arteries,NCA)的人群各45名. 通过实时血管回声跟踪(echo-tracking,ET)系统,获得双侧颈动脉的硬化指数(stiffness parameter,β)、压力-应变弹性指数(pressure-strain elastic modulus,Ep)、顺应性(arteri-al compliance,AC)和脉搏波传递速度(pulse-wave velocity,PWV). 对两组患者进行血清超敏C反应蛋白(high sensitivity c-re-active protein,Hs-CRP)水平测定,通过线性回归分析评价Hs-CRP和颈动脉硬化各项参数的相关性. 结果 CSF组β、Ep和PWV显著高于NCA组(β:11.80 ±3.19 vs 9.70 ±3.76,P<0.01;Ep:149.90 ±44.47 vs 130.10 ±41.56,P<0.05; PWV:7.40 ± 0.84 vs 7.00 ±1.08,P<0.05),AC低于NCA组(0.640 ±0.180 vs 0.760 ±0.192 ,P<0.01). CSF组Hs-CRP水平显著的高于NCA组(13.90 ±10.66 vs 9.30 ±6.33,P<0.05). Hs-CRP水平可能与 β(r=0.272,P=0.005)、 Ep(r=0.411,P=0.003)和PWV(r=0.452,P=0.001)具有一定的正相关性,但是和 AC(r=-0.293,P=0.025)呈负相关. 结论 在CSF患者,ET技术是一种简单、实用的评估颈动脉硬化的方法;CSF和颈动脉动脉硬化具有很好的相关性.
目的 研究冠狀動脈慢血流( coronary slow flow ,CSF)患者的頸動脈硬化情況. 方法 選取具有相似危險因素分層的CSF患者和冠狀動脈血流正常(normal coronary arteries,NCA)的人群各45名. 通過實時血管迴聲跟蹤(echo-tracking,ET)繫統,穫得雙側頸動脈的硬化指數(stiffness parameter,β)、壓力-應變彈性指數(pressure-strain elastic modulus,Ep)、順應性(arteri-al compliance,AC)和脈搏波傳遞速度(pulse-wave velocity,PWV). 對兩組患者進行血清超敏C反應蛋白(high sensitivity c-re-active protein,Hs-CRP)水平測定,通過線性迴歸分析評價Hs-CRP和頸動脈硬化各項參數的相關性. 結果 CSF組β、Ep和PWV顯著高于NCA組(β:11.80 ±3.19 vs 9.70 ±3.76,P<0.01;Ep:149.90 ±44.47 vs 130.10 ±41.56,P<0.05; PWV:7.40 ± 0.84 vs 7.00 ±1.08,P<0.05),AC低于NCA組(0.640 ±0.180 vs 0.760 ±0.192 ,P<0.01). CSF組Hs-CRP水平顯著的高于NCA組(13.90 ±10.66 vs 9.30 ±6.33,P<0.05). Hs-CRP水平可能與 β(r=0.272,P=0.005)、 Ep(r=0.411,P=0.003)和PWV(r=0.452,P=0.001)具有一定的正相關性,但是和 AC(r=-0.293,P=0.025)呈負相關. 結論 在CSF患者,ET技術是一種簡單、實用的評估頸動脈硬化的方法;CSF和頸動脈動脈硬化具有很好的相關性.
목적 연구관상동맥만혈류( coronary slow flow ,CSF)환자적경동맥경화정황. 방법 선취구유상사위험인소분층적CSF환자화관상동맥혈류정상(normal coronary arteries,NCA)적인군각45명. 통과실시혈관회성근종(echo-tracking,ET)계통,획득쌍측경동맥적경화지수(stiffness parameter,β)、압력-응변탄성지수(pressure-strain elastic modulus,Ep)、순응성(arteri-al compliance,AC)화맥박파전체속도(pulse-wave velocity,PWV). 대량조환자진행혈청초민C반응단백(high sensitivity c-re-active protein,Hs-CRP)수평측정,통과선성회귀분석평개Hs-CRP화경동맥경화각항삼수적상관성. 결과 CSF조β、Ep화PWV현저고우NCA조(β:11.80 ±3.19 vs 9.70 ±3.76,P<0.01;Ep:149.90 ±44.47 vs 130.10 ±41.56,P<0.05; PWV:7.40 ± 0.84 vs 7.00 ±1.08,P<0.05),AC저우NCA조(0.640 ±0.180 vs 0.760 ±0.192 ,P<0.01). CSF조Hs-CRP수평현저적고우NCA조(13.90 ±10.66 vs 9.30 ±6.33,P<0.05). Hs-CRP수평가능여 β(r=0.272,P=0.005)、 Ep(r=0.411,P=0.003)화PWV(r=0.452,P=0.001)구유일정적정상관성,단시화 AC(r=-0.293,P=0.025)정부상관. 결론 재CSF환자,ET기술시일충간단、실용적평고경동맥경화적방법;CSF화경동맥동맥경화구유흔호적상관성.
Objective To investigate the carotid arterial stiffness in patients with coronary slow flow ( CSF) .Methods forty-five patients with CSF and Forty -five persons having normal coronary arteries ( NCA) detected by coronary angiography with a similar distri-bution of risk factors were recruited .Stiffness parameter (β), pressure-strain elastic modulus (Ep), arterial compliance (AC) and lo-cal pulse-wave velocity (PWV) were obtained at the level of bilateral carotid artery by a real time echo -tracking system.Serum levels of high-sensitivity C-reactive protein ( hs-CRP) were measured in two groups of subjects .Linear regression analysis were performed to evaluate the correlation between hs -CRP and the parameters of the carotid artery stiffness .Results We found that stiffness parameter (β), Ep and PWV were significantly higher in CSF group those that of control group (β:11.80 ±3.19 vs 9.70 ±3.76,P<0.01;Ep:149.90 ±44.47 vs 130.10 ±41.56,P<0.05;PWV:7.40 ±0.84 vs 7.00 ±1.08,P<0.05), AC was lower than that of control group (0.640 ±0.180 vs 0.760 ±0.192 ,P<0.01).The levels of high-sensitivity C-reactive protein (hs-CRP) was significantly higher in CSF group than that of control group (13.90 ±10.66 vs 9.30 ±6.33,P<0.05).The levels of hs-CRP was positively correlated with theβ(r=0.272,P=0.005), Ep(r=0.411,P=0.003), and PWV(r=0.452,P=0.001), but negatively correlated with AC (r=-0.293,P=0.025).Conclusion Echo-tracking technology is a simple practical method to evaluate carotid artery stiffness in patients with CSF and correlation well with coronary slow flow and artery stiffness .
