CAJ | 학술논문

目的运用尿电解质肌酐比计算膳食盐,评价人群盐摄入量. 探讨尿电解质肌酐比、尿蛋白肌酐比( urinary pro-tein/creatinine ratio, TPCR)在体检和高血压患者中的应用价值. 方法检测948例(其中842名>50岁)健康体检者,616例住院高血压患者的尿钠、尿钾、尿总蛋白和空腹血清脂类项目,计算出尿钠肌酐比,尿钾肌酐比、尿钠钾比( Na+/K+)、TPCR和血清载脂蛋白B/A1(apoB/apoA1). 结果 948例体检者按年龄段分组比较中,尿TPCR在50~60岁年龄组与>70岁年龄组差异最明显(P=0.000);842例>50岁体检者不同性别间比较,尿盐、尿钾差异均有统计学意义(P=0.000);高血压组与体检组比较,尿TPCR、尿Na+/K+、尿盐差异有统计学意义( P=0 .000 );不同级别高血压的尿盐、Na+/K+及TPCR等指标均显著增高( P=0.000);616例高血压尿总蛋白与尿Na+/K+、尿Na+具有相关性;图中的尿TPCR浓度随年龄加大逐渐上升,高血压尿TPCR与尿Na+/K+均显著高于正常体检者. 结论通过尿电解质计算膳食盐,能简便有效反映人群盐摄入量的高低. 尿电解质肌酐比、尿TPCR与高血压的升级及年龄增大紧密相关.
목적 운용뇨전해질기항비계산선식염,평개인군염섭입량. 탐토뇨전해질기항비、뇨단백기항비( urinary pro-tein/creatinine ratio, TPCR)재체검화고혈압환자중적응용개치. 방법 검측948례(기중842명>50세)건강체검자,616례주원고혈압환자적뇨납、뇨갑、뇨총단백화공복혈청지류항목,계산출뇨납기항비,뇨갑기항비、뇨납갑비( Na+/K+)、TPCR화혈청재지단백B/A1(apoB/apoA1). 결과 948례체검자안년령단분조비교중,뇨TPCR재50~60세년령조여>70세년령조차이최명현(P=0.000);842례>50세체검자불동성별간비교,뇨염、뇨갑차이균유통계학의의(P=0.000);고혈압조여체검조비교,뇨TPCR、뇨Na+/K+、뇨염차이유통계학의의( P=0 .000 );불동급별고혈압적뇨염、Na+/K+급TPCR등지표균현저증고( P=0.000);616례고혈압뇨총단백여뇨Na+/K+、뇨Na+구유상관성;도중적뇨TPCR농도수년령가대축점상승,고혈압뇨TPCR여뇨Na+/K+균현저고우정상체검자. 결론 통과뇨전해질계산선식염,능간편유효반영인군염섭입량적고저. 뇨전해질기항비、뇨TPCR여고혈압적승급급년령증대긴밀상관.
Objective To investigate the salt intake of people by urine electrolytes /creatinine ratio calculating dietary salt and the application of urine electrolytes/creatinine ratio and urinary total protein/creatinine ratio on healthy people and hypertension .Methods Urinary sodium, urinary potassium, urine total protein and fasting serum lipids were detected in 948 (842 cases >50 years old) healthy people and 616 hypertensive Patients , and Urinary Sodium /Creatinine Ratio ( USCR) , urinary potassium creatinine ratio , urinary sodium/potassium (Na+/K+), urinary protein creatinine ratio (TPCR) and apoB/apoA1 were calculated.Results Urine TPCR of 50 to 60 years group showed significant difference compared to >70 years group by age grouping in 948 participants (P=0.000).Urine salt and urine potassium of female showed obvious difference compared to male in 842 cases >50 years healthy people (P =0.000).Urine TPCR, urine Na/K and urine salt were significantly highter in hypertension group than healthy group (P =0.000).Urine salt, Na+/K+and TPCR in different levels of hypertension were significantly difference (P =0.000).Urine TPCR was positively correlated with urine Na+/K+and USCR by linear correlation analysis in 616 hypertensive patients .Along the age escalating , urine TPCR increased gradually in figure, urine TPCR and urine Na +/K+were significantly higher in hypertension than health .Conclusion Urine electrolytes/creati-nine ratio is simple and effective to reflect the salt intake .Urine TPCR is closely related with hypertension upgrading and age escalating .