湖南师范大学学报（医学版）
湖南師範大學學報（醫學版）
호남사범대학학보（의학판）
Journal of Hunan Normal University (Medical Science)
2015年
4期
85-86,87
,共3页
赵聪亚%乔京贵%陈继龙%肖锦媛
趙聰亞%喬京貴%陳繼龍%肖錦媛
조총아%교경귀%진계룡%초금원
上腹痛综合征%心境稳定剂%抑酸药物
上腹痛綜閤徵%心境穩定劑%抑痠藥物
상복통종합정%심경은정제%억산약물
epigastric pain syndrome%mood stabilizer%acid suppression drugs
目的：观察比较“氟哌噻吨美利曲辛＋埃索美拉唑镁”法与单一使用埃索美拉唑镁法治疗功能性消化不良上腹痛综合征的临床效果。方法：根据纳入/排除标准共选取93例病例作为本次研究对象并随机分组；观察组采用“氟哌噻吨美利曲辛＋埃索美拉唑镁”法治疗，对照组单一使用埃索美拉唑镁法处理；比较两组患者治疗前后精神状况变化情况、上腹痛综合征（上腹部疼痛感、灼热感）症状评分变化情况。结果：观察组治疗后 HAMA 评分、HAMD 评分依次为（12.4±7.6）分、（7.1±4.9）分，均较对照组有明显降低；治疗后上腹部疼痛感评分、上腹部灼热感评分依次为（0.4±0.3）分、（0.3±0.2）分，均较对照组有显著降低。结论：氟哌噻吨美利曲辛、埃索美拉唑镁联合法较之单一使用抑酸药物治疗功能性消化不良上腹痛综合征临床效果更为理想，既使患者精神状况得到明显改善，又使患者上腹部疼痛感、灼热感得到有效缓解。
目的：觀察比較“氟哌噻噸美利麯辛＋埃索美拉唑鎂”法與單一使用埃索美拉唑鎂法治療功能性消化不良上腹痛綜閤徵的臨床效果。方法：根據納入/排除標準共選取93例病例作為本次研究對象併隨機分組；觀察組採用“氟哌噻噸美利麯辛＋埃索美拉唑鎂”法治療，對照組單一使用埃索美拉唑鎂法處理；比較兩組患者治療前後精神狀況變化情況、上腹痛綜閤徵（上腹部疼痛感、灼熱感）癥狀評分變化情況。結果：觀察組治療後 HAMA 評分、HAMD 評分依次為（12.4±7.6）分、（7.1±4.9）分，均較對照組有明顯降低；治療後上腹部疼痛感評分、上腹部灼熱感評分依次為（0.4±0.3）分、（0.3±0.2）分，均較對照組有顯著降低。結論：氟哌噻噸美利麯辛、埃索美拉唑鎂聯閤法較之單一使用抑痠藥物治療功能性消化不良上腹痛綜閤徵臨床效果更為理想，既使患者精神狀況得到明顯改善，又使患者上腹部疼痛感、灼熱感得到有效緩解。
목적：관찰비교“불고새둔미리곡신＋애색미랍서미”법여단일사용애색미랍서미법치료공능성소화불량상복통종합정적림상효과。방법：근거납입/배제표준공선취93례병례작위본차연구대상병수궤분조；관찰조채용“불고새둔미리곡신＋애색미랍서미”법치료，대조조단일사용애색미랍서미법처리；비교량조환자치료전후정신상황변화정황、상복통종합정（상복부동통감、작열감）증상평분변화정황。결과：관찰조치료후 HAMA 평분、HAMD 평분의차위（12.4±7.6）분、（7.1±4.9）분，균교대조조유명현강저；치료후상복부동통감평분、상복부작열감평분의차위（0.4±0.3）분、（0.3±0.2）분，균교대조조유현저강저。결론：불고새둔미리곡신、애색미랍서미연합법교지단일사용억산약물치료공능성소화불량상복통종합정림상효과경위이상，기사환자정신상황득도명현개선，우사환자상복부동통감、작열감득도유효완해。
ObjectiveTo observe and compare effects of treating functional dyspepsia epigastric pain syndrome by using flupenthixol melitracen and esomeprazole magnesium together and esomeprazole magnesium alone. MethodsChose 93 clinial cases as the observation objects according to incorporated into/exclusion criteria, and divided them into observation group and control group randomly. Used flupenthixol melitracen and esomeprazole magnesium together to treat these patients in observa-tion group, while adopted esomeprazole magnesium alone to treat control group’s patients; Then compared these two groups pa-tients’mental status changes and score changes of epigastric pain syndrome(including epigastric pain and burning heat sensa-tion) before and after treatment. ResultsObservation group’s HAMA score and HAMD score were (12.4±7.6) points and (7.1± 4.9) points respectively, the scores lower significantly when compared with control group’s after treatment. And epigastric pain score and burning heat sensation score were (0.4±0.3) points and (0.3±0.2) points after treatment, which lowered significantly when compared with control group’s. ConclusionIt is better to adopt flupenthixol melitracen and esomeprazole magnesium to-gether to treat functional dyspepsia epigastric pain syndrome, because it has better clinical effects compared with using esome-prazole magnesium alone. Not only it could improve patients’mental status significantly, but also release their epigastric pain and burning heat sensation effectively.
