中国药师
中國藥師
중국약사
China Pharmacist
2015年
11期
1980-1982
,共3页
黄晓燕%李玲%高容%胡亮%丁野%李文莉
黃曉燕%李玲%高容%鬍亮%丁野%李文莉
황효연%리령%고용%호량%정야%리문리
归芍地黄丸%山茱萸%马钱苷%莫诺苷%薄层色谱法%高效液相色谱法
歸芍地黃汍%山茱萸%馬錢苷%莫諾苷%薄層色譜法%高效液相色譜法
귀작지황환%산수유%마전감%막낙감%박층색보법%고효액상색보법
Guishao Dihuang pills%Corni Fructus%Morroniside%Loganin%TLC%HPLC
目的：：建立归芍地黄丸中山茱萸的定性和定量测定方法。方法：采用TLC对归芍地黄丸中山茱萸进行定性鉴别,并采用HPLC测定山茱萸中莫诺苷、马钱苷的含量。结果： TLC色谱斑点清晰,分离度好,专属性强；莫诺苷对照品在0.010~2.620μg范围内线性关系良好(r =0.9999),平均回收率为102.75%,RSD 为1.40%(n =6)。马钱苷对照品在0.009~2.170μg范围内线性关系良好(r=0.9999),平均回收率为103.59%,RSD为1.10%(n=6)。结论：本方法准确、简单、可行,重复性好,可有效控制该制剂中山茱萸的质量。
目的：：建立歸芍地黃汍中山茱萸的定性和定量測定方法。方法：採用TLC對歸芍地黃汍中山茱萸進行定性鑒彆,併採用HPLC測定山茱萸中莫諾苷、馬錢苷的含量。結果： TLC色譜斑點清晰,分離度好,專屬性彊；莫諾苷對照品在0.010~2.620μg範圍內線性關繫良好(r =0.9999),平均迴收率為102.75%,RSD 為1.40%(n =6)。馬錢苷對照品在0.009~2.170μg範圍內線性關繫良好(r=0.9999),平均迴收率為103.59%,RSD為1.10%(n=6)。結論：本方法準確、簡單、可行,重複性好,可有效控製該製劑中山茱萸的質量。
목적：：건립귀작지황환중산수유적정성화정량측정방법。방법：채용TLC대귀작지황환중산수유진행정성감별,병채용HPLC측정산수유중막낙감、마전감적함량。결과： TLC색보반점청석,분리도호,전속성강；막낙감대조품재0.010~2.620μg범위내선성관계량호(r =0.9999),평균회수솔위102.75%,RSD 위1.40%(n =6)。마전감대조품재0.009~2.170μg범위내선성관계량호(r=0.9999),평균회수솔위103.59%,RSD위1.10%(n=6)。결론：본방법준학、간단、가행,중복성호,가유효공제해제제중산수유적질량。
Objective:To establish the qualitative and quantitative methods for Corni Fructus in Guishao Dihuang pills. Methods:A TLC method was used to identify morroniside and loganin. An HPLC method was used to determine the content of morroniside and lo-ganin in Corni Fructus. Results:The TLC spots were clear with good separation and specificity. The linear range of morroniside was within 0. 010-2. 620 μg (r=0. 999 9) and the average recovery was 102. 75% (RSD=1. 40%, n=6). The linear range of loganin was within 0.009-2.170 μg (r =0.999 9), and the average recovery was 103.59% (RSD =1.10%, n =6). Conclusion: The method is accurate, simple and feasible with good repeatability, which can be used for the quality control of Corni Fructus in the prepa-ration.
