CAJ | 학술논문

目的：评估坦索罗辛辅助输尿管镜气压弹道碎石术( URSL)治疗输尿管下段结石的有效性。方法筛选输尿管下段结石患者120例，按就诊先后顺序分为观察组和对照组，各60例。2组所有患者均进行了输尿管镜碎石术，术后观察组予以坦索罗辛及传统的药物治疗(包括液体冲击治疗、抗炎、镇痛)，对照组予以安慰剂及传统治疗。记录2组患者术后发生的腹痛情况、下尿路症状、止痛药应用以及自然排石的时间。用SPSS 13.0对2组数据用统计学分析。结果2组在结石清除率方面比较无明显差异(P>0.05)，但观察组的排石时间更短(P<0.05)，此外，观察组下尿路症状的发生率，止痛药应用率，腹痛发生的平均次数均明显低于对照组(P<0.05)。结论输尿管镜碎石术后应用坦索罗辛可以明显降低腹痛症状的发生和止痛药的需要并缩短结石的排出时间。
목적：평고탄색라신보조수뇨관경기압탄도쇄석술( URSL)치료수뇨관하단결석적유효성。방법사선수뇨관하단결석환자120례，안취진선후순서분위관찰조화대조조，각60례。2조소유환자균진행료수뇨관경쇄석술，술후관찰조여이탄색라신급전통적약물치료(포괄액체충격치료、항염、진통)，대조조여이안위제급전통치료。기록2조환자술후발생적복통정황、하뇨로증상、지통약응용이급자연배석적시간。용SPSS 13.0대2조수거용통계학분석。결과2조재결석청제솔방면비교무명현차이(P>0.05)，단관찰조적배석시간경단(P<0.05)，차외，관찰조하뇨로증상적발생솔，지통약응용솔，복통발생적평균차수균명현저우대조조(P<0.05)。결론수뇨관경쇄석술후응용탄색라신가이명현강저복통증상적발생화지통약적수요병축단결석적배출시간。
Objective To investigate the efficacy of tamsulosin in the distal ureter calculi expelling after ureteroscopic lithotripsy. Methods A total of 120 patients with distal ureteral calculi were enrolled and randomly divided into the observation group and the control group with 60 patients in each group. Patients in the observation group received tamsulosin and traditional treatment ( including liquid impact therapy,anti-inflammatory and analgesia) ,while patients in the control group received placebo and traditional treatment after operation. The number of colic episodes,lower urinary tract symptoms,analgesic dosage,and time of calculus removing were recorded and all the data were statistically analysed through software SPSS 13. 0. Results There was no singinificant difference between the two groups in the rate of calculus removing (P>0. 05), but it took less time in the observation group (P<0. 05). In addition, it was of less low urinary tract symptoms, low-er rate of analgesic usage and colic episodes in the observation group with statistically significant differences compared with the control group (P<0. 05). Conclusion The application of tamsulosin after ureteroscopic lithotripsy can reduce the rate of colic episodes and analgesic dosage and time of calculus removing.