CAJ | 학술논문

1例57岁女性患者,因肺癌伴右颈淋巴结增大和颜面浮肿入院治疗.给予地塞米松预处理后,静脉滴注紫杉醇30 mg化疗,患者无明显不适.之后给予紫杉醇90 mg,ivgtt,qd,用药17 h后,患者出现恶心,胸背部瘙痒,前胸散在粟粒样浅红色斑疹.给予苯海拉明(20 mg,im)、西替利嗪(10 mg)和外擦炉甘石洗剂抗过敏治疗,皮疹未见好转,逐渐蔓延至全身.将抗过敏治疗方案调整为氯苯那敏(4 mg)、苯海拉明(20 mg,im)和氢化可的松琥珀酸钠(400 mg,ivgtt)等进行综合治疗,患者皮疹逐渐好转,18 d后患者皮疹消退.
1례57세녀성환자,인폐암반우경림파결증대화안면부종입원치료.급여지새미송예처리후,정맥적주자삼순30 mg화료,환자무명현불괄.지후급여자삼순90 mg,ivgtt,qd,용약17 h후,환자출현악심,흉배부소양,전흉산재속립양천홍색반진.급여분해랍명(20 mg,im)、서체리진(10 mg)화외찰로감석세제항과민치료,피진미견호전,축점만연지전신.장항과민치료방안조정위록분나민(4 mg)、분해랍명(20 mg,im)화경화가적송호박산납(400 mg,ivgtt)등진행종합치료,환자피진축점호전,18 d후환자피진소퇴.
One 57-year-old female lung cancer patient with lymph node enlargement and facial edema was admitted to hospital. After pretreatment of dexamethasone, paclitaxel (30 mg, ivgtt, st) was given to her and then paclitaxel (90 mg, ivgtt, qd) followed. Seventeen hours later, the patient developed chest and back itching, nausea and scattered miliary plum macula in prothorax. The rash spreaded all over the body even after the antianaphylactic treatment with diphenhydramine (20 mg, im), cetirizine (10 mg) and calamine lotion. And then chlorpheniramine (4 mg), diphenhydramine (20 mg, im) and hydrocortisone sodium succinate (400 mg, ivgtt) were given to her. The patient was getting better gradually and the rash disappeared 18 days later.