中西医结合心血管病电子杂志
中西醫結閤心血管病電子雜誌
중서의결합심혈관병전자잡지
Cardiovascular Disease Journal of Integrated Traditional Chinese and Western Medicine(Electronic)
2015年
12期
47-49
,共3页
大剂量%氯吡格雷%冠心病%介入治疗
大劑量%氯吡格雷%冠心病%介入治療
대제량%록필격뢰%관심병%개입치료
Large dose%Chlorine clopidogrel%Coronary artery disease%Interventional therapy
目的 观察冠心病患者采用大剂量氯吡格雷进行介入治疗的临床应用价值.方法 选择2014年4月~2015年11月在我院进行治疗的冠心病患者150例为研究对象,随机分为对照组与观察组,各75例.对照组采用标准量的氯吡格雷进行治疗,观察组采用大剂量的氯吡格雷介入治疗,观察两组患者的疗效、抗血小板凝集效果及不良反应情况.结果 观察组治疗有效率为98.67%,明显高于对照组的89.33%,差异有统计学意义(P<0.05);介入治疗后,观察组的血小板聚集率明显比对照组的低,差异有统计学意义(P<0.05);观察组的不良反应出现情况明显比对照组少,差异有统计学意义(P<0.05),治疗后1个月内复发情况,观察组也少于对照组,差异有统计学意义(P<0.05).结论 大剂量的氯吡格雷对冠心病患者的介入治疗可更有效提高疗效,对血小板的抗凝集作用更强,值得临床推广.
目的 觀察冠心病患者採用大劑量氯吡格雷進行介入治療的臨床應用價值.方法 選擇2014年4月~2015年11月在我院進行治療的冠心病患者150例為研究對象,隨機分為對照組與觀察組,各75例.對照組採用標準量的氯吡格雷進行治療,觀察組採用大劑量的氯吡格雷介入治療,觀察兩組患者的療效、抗血小闆凝集效果及不良反應情況.結果 觀察組治療有效率為98.67%,明顯高于對照組的89.33%,差異有統計學意義(P<0.05);介入治療後,觀察組的血小闆聚集率明顯比對照組的低,差異有統計學意義(P<0.05);觀察組的不良反應齣現情況明顯比對照組少,差異有統計學意義(P<0.05),治療後1箇月內複髮情況,觀察組也少于對照組,差異有統計學意義(P<0.05).結論 大劑量的氯吡格雷對冠心病患者的介入治療可更有效提高療效,對血小闆的抗凝集作用更彊,值得臨床推廣.
목적 관찰관심병환자채용대제량록필격뢰진행개입치료적림상응용개치.방법 선택2014년4월~2015년11월재아원진행치료적관심병환자150례위연구대상,수궤분위대조조여관찰조,각75례.대조조채용표준량적록필격뢰진행치료,관찰조채용대제량적록필격뢰개입치료,관찰량조환자적료효、항혈소판응집효과급불량반응정황.결과 관찰조치료유효솔위98.67%,명현고우대조조적89.33%,차이유통계학의의(P<0.05);개입치료후,관찰조적혈소판취집솔명현비대조조적저,차이유통계학의의(P<0.05);관찰조적불량반응출현정황명현비대조조소,차이유통계학의의(P<0.05),치료후1개월내복발정황,관찰조야소우대조조,차이유통계학의의(P<0.05).결론 대제량적록필격뢰대관심병환자적개입치료가경유효제고료효,대혈소판적항응집작용경강,치득림상추엄.
Objective The clinical application value of large dose clopidogrel in the treatment of patients with coronary heart disease.Methods Select from April 2014 to January 2015 in our hospital for treatment of 150 cases of coronary heart disease patients, the system grouping divides it into two groups, the control group and the observation group, 75 cases in each group, the control group using the standard amount of clopidogrel treatment, and the observation group were treated with large doses of clopidogrel intervention observed the therapeutic effect of two groups of patients, antiplatelet effect and adverse reaction of.Results Observation group, the effective rate is 98.67%, significantly higher than the control group of 89.33% (P<0.05); after interventional therapy were observed group of patients with platelet aggregation rate significantly than the control group low(P<0.05), observation group of patients with adverse reactions appeared significantly than that in the control group (P<0.05). After treatment for 1 month recurrence within observed group was less than that in the control group(P<0.05),Conclusion Large dose of clopidogrel for patients with coronary heart disease intervention can more effectively improve the treatment effect of patients, the platelet agglutination stronger.
