CAJ | 학술논문

目的探讨内镜下射频消融术治疗食管和胃的低级别上皮内瘤变的有效性及安全性.方法回顾性分析解放军总医院消化内镜中心2014年10月至2015年1月行内镜检查,经病理证实为食管或胃低级别上皮内瘤变的21例患者纳入研究,经门诊行内镜下射频消融治疗,其中食管部病变射频消融2次,胃部病变射频消融3次,术后采用Wang-Baker面部表情量表进行疼痛评分,治疗后1个月进行内镜复查. 结果 21例共计31个低级别上皮内瘤变病灶纳入研究. 16例共计23个低级别上皮内瘤变病灶进行了复查,其中14例患者,21个病灶经射频治疗后消失,病灶消除率91 .30%(21/23);2例患者2个低级别上皮内瘤变病灶出现残留,病灶残留率8.70%(2/23). 16例复查患者病灶治疗部位黏膜均愈合,术后腹痛为主要并发症. 结论内镜下射频消融术治疗食管和胃低级别上皮内瘤变是安全、有效、并发症小、可门诊治疗的一种新方法.
목적 탐토내경하사빈소융술치료식관화위적저급별상피내류변적유효성급안전성.방법 회고성분석해방군총의원소화내경중심2014년10월지2015년1월행내경검사,경병리증실위식관혹위저급별상피내류변적21례환자납입연구,경문진행내경하사빈소융치료,기중식관부병변사빈소융2차,위부병변사빈소융3차,술후채용Wang-Baker면부표정량표진행동통평분,치료후1개월진행내경복사. 결과 21례공계31개저급별상피내류변병조납입연구. 16례공계23개저급별상피내류변병조진행료복사,기중14례환자,21개병조경사빈치료후소실,병조소제솔91 .30%(21/23);2례환자2개저급별상피내류변병조출현잔류,병조잔류솔8.70%(2/23). 16례복사환자병조치료부위점막균유합,술후복통위주요병발증. 결론 내경하사빈소융술치료식관화위저급별상피내류변시안전、유효、병발증소、가문진치료적일충신방법.
Objective To evaluate the efficacy and safety of radiofrequency ablation ( RFA) for esophageal and gastric low-grade intraepithelial neoplasia ( LIN) .Methods We retrospectively enrolled 21 patients with LIN of esophagus and stomach who were treated with RFA under endoscopic at the General Hospital of PLA from October 2014 to January 2015 .Two pulses were used to ablate the esophageal lesions and three pulses were used to ablate the gastric lesions .Pain scores were recorded using Wang-Baker facial pain scale.A month later, patients underwent regular endoscopy follow-ups.Results A total of 31 LIN lesions of 21 patients were included in the study .Twenty-three lesions of 16 patients underwent endoscopy follow-ups after 1 month.The lesions elimination rate was 91.30%(21/23)and the lesions residual rate was 8.70%(2/23).The RFA treatment lesions of 16 patients healed by endoscopy follow-up and postoperative pain was the main complications .Conclusion RFA is considered to be safe and effective , which can be performed in the outpatient service .