CAJ | 학술논문

目的：探讨经直肠超声检测前列腺体积结合前列腺特异性抗原检测对于前列腺癌的诊断价值。方法回顾性分析我院2011年1月-2013年12月间收治的52例前列腺疾病患者的临床资料，入院后均给予经直肠超声检查，后经过前列腺穿刺活检或术后病理证实，其中有21例确诊为前列腺癌设为 PCa 组，中重度前列腺增生31例设为BPH 组，比较两组经直肠超声检测的声像特点及其 PSA 水平。结果PCa 组患者前列腺体积相比于 BPH 患者明显减小，t＝3．901，P ＜0．05，其异常血流信号发生率明显升高，χ2＝15．511，P ＜0．05，PCa 组患者的 PSA 值相比于 BPH组患者显著升高，t＝18．470，其＞10 ng／ml 区段的分布率显著高于对照组，χ2＝23．862，P ＜0．05，＜4 ng／ml 的分布率显著低于对照组，χ2＝26．870，P ＜0．05。结论较小的前列腺体积以及异常的血流信号是前列腺癌直肠超声的检测特点，PSA 是前列腺癌的敏感性检测指标，二者联合应用于前列腺癌的诊断具有极高的临床价值。
목적：탐토경직장초성검측전렬선체적결합전렬선특이성항원검측대우전렬선암적진단개치。방법회고성분석아원2011년1월-2013년12월간수치적52례전렬선질병환자적림상자료，입원후균급여경직장초성검사，후경과전렬선천자활검혹술후병리증실，기중유21례학진위전렬선암설위 PCa 조，중중도전렬선증생31례설위BPH 조，비교량조경직장초성검측적성상특점급기 PSA 수평。결과PCa 조환자전렬선체적상비우 BPH 환자명현감소，t＝3．901，P ＜0．05，기이상혈류신호발생솔명현승고，χ2＝15．511，P ＜0．05，PCa 조환자적 PSA 치상비우 BPH조환자현저승고，t＝18．470，기＞10 ng／ml 구단적분포솔현저고우대조조，χ2＝23．862，P ＜0．05，＜4 ng／ml 적분포솔현저저우대조조，χ2＝26．870，P ＜0．05。결론교소적전렬선체적이급이상적혈류신호시전렬선암직장초성적검측특점，PSA 시전렬선암적민감성검측지표，이자연합응용우전렬선암적진단구유겁고적림상개치。
Objective Study the clinical value of using prostate volume detecting via transrectal ultrasound combine PSA level in the diagnosis for prostate cancer.Methods Made a retrospective analysis for clinical data of 52 patients with prostate disease in our hospital from January 2011-December 2013,after hospital all of them received transrectal ultrasound detection,after the prostate biopsy or postoperative pathology,of which 21 patients was diagnosed with prostate cancer and set as PCa group,31 patients was diagnosed with moderately of severe hyperplasia and set as BPH group,compared acoustic image characteristics by transrectal ultrasound detection and the PSA level in two groups .Re-sults The prostate volume of PCa patients is lower than patients with BPH,t=3.901,P <0.05,the incidence rate of abnormal blood flow signal was significantly higher than that of BPH group,χ2 =15.511,P < 0.05,PSA level of PCa group was significant higher than patients in BPH group,t = 18.470,interval distribution rate of > 10 is significantly higher than in the control group,χ2 =23.862,P <0.05,interval distribution rate of < 4 ng/ml was significantly lower than the control group,χ2 =26.870,P <0.05).Conclusion Smaller volume of the prostate and abnormal blood flow signals of transrectal ultrasound features of prostate cancer,PSA is the sensitivity detection index of prostate cancer, making a combination of them rise the diagnosis rate of prostate cancer.