中国临床药理学杂志
中國臨床藥理學雜誌
중국림상약이학잡지
The Chinese Journal of Clinical Pharmacology
2015年
19期
1898-1900
,共3页
腹部创伤%感染创面%封闭式负压引流%疼痛%生活质量
腹部創傷%感染創麵%封閉式負壓引流%疼痛%生活質量
복부창상%감염창면%봉폐식부압인류%동통%생활질량
abdominal trauma%wound infection%closed negative pressure drainage%pain%quality of life
目的 评价封闭式负压引流治疗老年腹部创伤及感染创面的临床疗效和安全性. 方法 将42例老年腹部创伤及感染创面患者随机分为试验组21例和对照组21例. 对照组予以红霉素软膏每日涂抹2次和常规换药处理;试验组予以封闭式负压引流治疗,并配合抗菌治疗. 用视觉模拟评分量表( VAS)比较治疗前后疼痛情况,用生活质量评分量表( QOL)比较治疗前后生活质量. 比较2组患者的日引流量、换药次数、住院天数、1 ,2 ,3周的感染控制情况和不良反应情况. 结果 治疗后,试验组VAS评分(4.9 ±1.8)分低于对照组(6.5 ±2.2)分( P <0.05 ). 治疗后,试验组 QOL 评分( 95.1 ±3.9 ) 分高于对照组(82.8 ±10.7)分(P<0.01). 试验组日引流量(51.93 ±10.14)mL高于对照组(13.91 ±5.22 ) mL ( P<0.01 ). 试验组换药次数( 9.08 ±2.72 )次、住院天数(20.56 ±4.95 ) d 均少于对照组换药次数( 18.07 ±5.54 )次、住院天数(30.91 ±7.80)d(P<0.01). 试验组感染控制率95.21%优于对照组66.74%( P<0.05 ). 试验组不良反应发生率为0显著低于对照组23.80%( P<0.01 ).结论 封闭式负压引流在老年腹部创伤及感染创面的治疗中能有效地缓解患者的疼痛,加快创面愈合,有效控制感染,促进预后,改善患者的生活质量.
目的 評價封閉式負壓引流治療老年腹部創傷及感染創麵的臨床療效和安全性. 方法 將42例老年腹部創傷及感染創麵患者隨機分為試驗組21例和對照組21例. 對照組予以紅黴素軟膏每日塗抹2次和常規換藥處理;試驗組予以封閉式負壓引流治療,併配閤抗菌治療. 用視覺模擬評分量錶( VAS)比較治療前後疼痛情況,用生活質量評分量錶( QOL)比較治療前後生活質量. 比較2組患者的日引流量、換藥次數、住院天數、1 ,2 ,3週的感染控製情況和不良反應情況. 結果 治療後,試驗組VAS評分(4.9 ±1.8)分低于對照組(6.5 ±2.2)分( P <0.05 ). 治療後,試驗組 QOL 評分( 95.1 ±3.9 ) 分高于對照組(82.8 ±10.7)分(P<0.01). 試驗組日引流量(51.93 ±10.14)mL高于對照組(13.91 ±5.22 ) mL ( P<0.01 ). 試驗組換藥次數( 9.08 ±2.72 )次、住院天數(20.56 ±4.95 ) d 均少于對照組換藥次數( 18.07 ±5.54 )次、住院天數(30.91 ±7.80)d(P<0.01). 試驗組感染控製率95.21%優于對照組66.74%( P<0.05 ). 試驗組不良反應髮生率為0顯著低于對照組23.80%( P<0.01 ).結論 封閉式負壓引流在老年腹部創傷及感染創麵的治療中能有效地緩解患者的疼痛,加快創麵愈閤,有效控製感染,促進預後,改善患者的生活質量.
목적 평개봉폐식부압인류치료노년복부창상급감염창면적림상료효화안전성. 방법 장42례노년복부창상급감염창면환자수궤분위시험조21례화대조조21례. 대조조여이홍매소연고매일도말2차화상규환약처리;시험조여이봉폐식부압인류치료,병배합항균치료. 용시각모의평분량표( VAS)비교치료전후동통정황,용생활질량평분량표( QOL)비교치료전후생활질량. 비교2조환자적일인류량、환약차수、주원천수、1 ,2 ,3주적감염공제정황화불량반응정황. 결과 치료후,시험조VAS평분(4.9 ±1.8)분저우대조조(6.5 ±2.2)분( P <0.05 ). 치료후,시험조 QOL 평분( 95.1 ±3.9 ) 분고우대조조(82.8 ±10.7)분(P<0.01). 시험조일인류량(51.93 ±10.14)mL고우대조조(13.91 ±5.22 ) mL ( P<0.01 ). 시험조환약차수( 9.08 ±2.72 )차、주원천수(20.56 ±4.95 ) d 균소우대조조환약차수( 18.07 ±5.54 )차、주원천수(30.91 ±7.80)d(P<0.01). 시험조감염공제솔95.21%우우대조조66.74%( P<0.05 ). 시험조불량반응발생솔위0현저저우대조조23.80%( P<0.01 ).결론 봉폐식부압인류재노년복부창상급감염창면적치료중능유효지완해환자적동통,가쾌창면유합,유효공제감염,촉진예후,개선환자적생활질량.
Objective To investigate the curative effect of closed nega-tive pressure drainage in treatment of elderly patients with abdominal trauma and wound infection .Methods Fourty-two cases of elderly pa-tients with abdominal trauma and wound infection were randomly divided into control group (n=21) and treatment group (n=21).Control group was given erythromycin ointment twice a day and conventional dressing treatment.Treatment group was taken the treatment of closed negative pressure drainage and antibacterial therapy .The pain situation as well as the life quality score before and after treatment by visual analogue rating scale (VAS) was compared.Besides, the daily drainage, dressing, days of hospitalization, infection control situation 1,2,3 weeks and adverse drug reactions between the two groups were compared .Results After treatment, the VAS score (4.9 ±1.8) points of treatment group was sig-nificantly lower than that of the control group with VAS score (6.5 ±2.2 ) ( P <0.05 ) . The drainage ( 51.93 ±10.14 ) mL of treatment group was higher than that of the control group ( P <0.01 ) .The bandage times (9.08+2.72) and hospital stay (20.56+4.95 ) d of treatment group were less than those of the control group with dressing change times (18.07+5.54 ) and hospital stay ( 30.91+7.80 ) d ( P<0.01 ) .infection control rate of treatment group (95.21%) was higher that of control group (66.74%)(P<0.05).After treatment, the life quality of treatment group ( 95.1+3.9 ) is higher than that of control group ( 82.8+10.7 ) , with significant difference (P<0.01).The incidences of adverse reactions in treatment group was 0, the control group was 23.80%(5/21), difference between groups was statistically significant (P<0.05).Conclusion The closed negative pressure drainage has a high application value in the treatment of senile abdominal trauma and infection in the wound , which can ease the pain , accelerate wound healing , control infection effectively , improves prognosis , improve the life quality of the patients.
