CAJ | 학술논문

目的：探讨小剂量按时口服他达拉非联合苁蓉益肾颗粒治疗肾阳虚型 ED（Erectile Dysfunc-tion）的临床疗效。方法：选取80例中医辨证属肾阳虚的 ED 患者，随机分为治疗组和对照组，每组各40例。对照组单纯口服他达拉非，治疗组在口服他达拉非的基础上加用苁蓉益肾颗粒，两组均用药治疗3个月。分别对治疗前后的国际勃起功能指数（IIEF －5）评分、插入阴道成功率、完成性交成功率、总有效率进行统计学分析。结果：治疗组和对照组在 IIEF －5评分、插入阴道成功率、完成性交成功率、总有效率方面均较治疗前增加，差异具有统计学意义（P ＜0．05），但治疗组治疗后上述各指标均显著高于对照组治疗后，差异具有统计学意义（P ＜0．05）。结论：小剂量按时口服他达拉非联合苁蓉益肾颗粒治疗肾阳虚型 ED 效果显著。
목적：탐토소제량안시구복타체랍비연합종용익신과립치료신양허형 ED（Erectile Dysfunc-tion）적림상료효。방법：선취80례중의변증속신양허적 ED 환자，수궤분위치료조화대조조，매조각40례。대조조단순구복타체랍비，치료조재구복타체랍비적기출상가용종용익신과립，량조균용약치료3개월。분별대치료전후적국제발기공능지수（IIEF －5）평분、삽입음도성공솔、완성성교성공솔、총유효솔진행통계학분석。결과：치료조화대조조재 IIEF －5평분、삽입음도성공솔、완성성교성공솔、총유효솔방면균교치료전증가，차이구유통계학의의（P ＜0．05），단치료조치료후상술각지표균현저고우대조조치료후，차이구유통계학의의（P ＜0．05）。결론：소제량안시구복타체랍비연합종용익신과립치료신양허형 ED 효과현저。
Objectives:To explore the clinical effect of low dose tadalafil combined with Congrong Yishen granule in the treatment of kidney -yang deficiency type erectile dysfunction (ED).Methods:80 ED patients with TCMsyndrome of kidney -yang deficiency were randomly divided into treatment group and control group,with 40 cases in each group.The control group was treated with oral tadalafil and the treatment group was treated with oral tadalafil and Congrong Yishen granule.After 3 months treatment,before and after the treatment,the IIEF -5 score,success rate of vagina -inserting,sexual intercourse success rate and total efficiency rate of the two groups were analyzed.Results:The IIEF -5 score,success rate of vagina -inserting,sexual intercourse success rate and total efficiency rate of the two groups were increased compared with these before the treatment,with statistically sig-nificant difference (P <0.05),but after treatment,all of the above indicators of the treatment group were signifi-cantly higher than those of the control group,with statistically significant difference (P <0.05).Conclusion:The clinical effect of low dose tadalafil combined with Congrong Yishen granule in the treatment of kidney -yang defi-ciency type ED is remarkable.