CAJ | 학술논문

目的：探讨艾滋病患者服药依从性的影响因素，对患者进行干预提高患者用药依从性。方法：选取艾滋病患者577例，根据其用药依从情况分为两组。对两组患者社会人口学因素、药物因素以及治疗因素进行调查并进行统计和比较。结果：依从良好组患者年龄、病程、用药种类以及药物应用时间均明显低于依从差组，年收入明显高于依从差组。两组比较差异有统计学意义（P ＜0．05）。依从良好组患者中女性、高中及以下文化程度、已婚者、对疾病知识和药物知识了解、心理健康者、医疗服务及医患关系良好、家属配合良好以及非自费者均明显多于依从差者；酗酒、药物滥用以及有药物不良反应者均明显少于服药依从性差者。上述比较两组差异有统计学意义（P ＜0．05）。经 Logistic 回归多因素分析，患者的年龄、年收入、药物应用种类和时间、对疾病和药物知识掌握情况、是否存在不良反应、家属配合程度以及医疗费用支付方式是影响艾滋病患者服药依从性的独立危险因素（P ＜0．05）。结论：艾滋病患者大多服药依从性良好，而影响其用药依从性的因素多样，包括患者自身因素，也包括药物因素和治疗因素，在临床工作中可以通过对影响因素进行干预而提高患者的服药依从性。
목적：탐토애자병환자복약의종성적영향인소，대환자진행간예제고환자용약의종성。방법：선취애자병환자577례，근거기용약의종정황분위량조。대량조환자사회인구학인소、약물인소이급치료인소진행조사병진행통계화비교。결과：의종량호조환자년령、병정、용약충류이급약물응용시간균명현저우의종차조，년수입명현고우의종차조。량조비교차이유통계학의의（P ＜0．05）。의종량호조환자중녀성、고중급이하문화정도、이혼자、대질병지식화약물지식료해、심리건강자、의료복무급의환관계량호、가속배합량호이급비자비자균명현다우의종차자；후주、약물람용이급유약물불량반응자균명현소우복약의종성차자。상술비교량조차이유통계학의의（P ＜0．05）。경 Logistic 회귀다인소분석，환자적년령、년수입、약물응용충류화시간、대질병화약물지식장악정황、시부존재불량반응、가속배합정도이급의료비용지부방식시영향애자병환자복약의종성적독립위험인소（P ＜0．05）。결론：애자병환자대다복약의종성량호，이영향기용약의종성적인소다양，포괄환자자신인소，야포괄약물인소화치료인소，재림상공작중가이통과대영향인소진행간예이제고환자적복약의종성。
Objectives:To investigate the AIDS medication compliance factors,intervention patients im-prove patient medication compliance.Methods:577 cases of AIDS,according to their medication adherence were divided into two groups.For sociodemographic factors,drug factors,and treatment factors were investigated and the two groups were statistically and compared.Results:The age of good compliance group,duration,types of medica-tion and drug use were significantly lower than the compliance time difference between groups was significantly high-er than the annual income of poor adherence group.The difference was statistically significant (P <0.05).Good compliance female patient group,high school education or less,married,disease knowledge and knowledge about drugs,mental health person,medical services and doctor -patient relationships,families with good and caught his own expense significantly more than non -poor compliance persons;alcoholism,drug abuse,and there is signifi-cantly less adverse drug reactions caught with poor medication compliance.The comparison between the two groups was statistically significant (P <0.05).Logistic regression multivariate analysis,age,annual income,type and timing of drug use,disease and drug knowledge to grasp the situation,the existence of adverse reactions,as well as with the families of the extent of the impact of payment of medical expenses AIDS medication compliance independ-ence risk factors (P <0.05).Conclusions:Most patients with AIDS medication compliance is good,and factors affecting medication adherence and more want,including the patient’s own factors,including drug factors and treat-ment factors in clinical work carried out by the intervention of factors improve patient medication compliance.