中国性科学
中國性科學
중국성과학
Chinese Journal of Human Sexuality
2015年
10期
82-85
,共4页
周伟%李新伟%张群芝
週偉%李新偉%張群芝
주위%리신위%장군지
男性不育%染色体异常%核型分析
男性不育%染色體異常%覈型分析
남성불육%염색체이상%핵형분석
Male infertility%Chromosomal abnormality%Karyrotype analysis
目的:对男性不育患者进行染色体核型的检测,探讨男性不育与染色体核型异常的关系。方法:按常规方法制作染色体标本的方法,对122例男性不育患者进行核型分析。结果:共检出染色体异常17例,异常率为13.93%。其中性染色体异常12例,占男性不育患者的9.84%,常染色体异常5例,占男性不育患者的4.10%。在所有的核型中,Klinefelter 综合征的发生率最高,占异常核型的23.53%。结论:染色体异常是导致男性不育的重要原因之一,染色体核型分析对男性不育患者的诊断和治疗具有重要的指导意义。
目的:對男性不育患者進行染色體覈型的檢測,探討男性不育與染色體覈型異常的關繫。方法:按常規方法製作染色體標本的方法,對122例男性不育患者進行覈型分析。結果:共檢齣染色體異常17例,異常率為13.93%。其中性染色體異常12例,佔男性不育患者的9.84%,常染色體異常5例,佔男性不育患者的4.10%。在所有的覈型中,Klinefelter 綜閤徵的髮生率最高,佔異常覈型的23.53%。結論:染色體異常是導緻男性不育的重要原因之一,染色體覈型分析對男性不育患者的診斷和治療具有重要的指導意義。
목적:대남성불육환자진행염색체핵형적검측,탐토남성불육여염색체핵형이상적관계。방법:안상규방법제작염색체표본적방법,대122례남성불육환자진행핵형분석。결과:공검출염색체이상17례,이상솔위13.93%。기중성염색체이상12례,점남성불육환자적9.84%,상염색체이상5례,점남성불육환자적4.10%。재소유적핵형중,Klinefelter 종합정적발생솔최고,점이상핵형적23.53%。결론:염색체이상시도치남성불육적중요원인지일,염색체핵형분석대남성불육환자적진단화치료구유중요적지도의의。
Objectives:To analyze the karyotypes of infertile male patients so as to investigate the relation-ship between male infertility and chromosome abnormalities.Methods:The chromosome karyotypes of 1 22 male in-fertile patients were analyzed by routinely cultured peripheral blood lymphocytes.Results:There were 1 7 cases of abnormal karyotypes which accounted for 1 3.93%,including 1 2 (9.84%)cases of sex abnormal karyotype and 5 (4.1 0%)cases of autosome abnormal karyotype.The klinefelter syndrome was the most common disease caused by abnormal karyotype and the ratio was 23.53% in all the abnormal karyotypes.Conclusion:Chromosome abnormali-ty is an important cause of male infertility.Karyotype analysis is important for the diagnosis and treatment of male infertility.