CAJ | 학술논문

目的：探讨胸部肿瘤患者在不同时间段、不同类型肿瘤、不同治疗方法下调强放疗动态心电图变化情况。方法：选取2010年4月－2013年4月95例胸部肿瘤患者为研究对象，按照肿瘤类型分成肺癌组35例，乳腺癌组29例，食管癌组31例；按照治疗方法分成单纯放疗组26例，同步放化组34例，序贯放化组35例，分别在治疗前、治疗后和治疗结束6个月后观察动态心电图变化情况。结果：治疗后和治疗前在偶发室（房）性心律失常、ST －T 段改变动态心电图异常发生率上比较差异有统计学意义（P ＜0．05），而治疗结束6个月后和治疗前在偶发室（房）性心律失常、ST －T 段改变动态心电图异常发生率比较差异无统计学意义（P＞0．05）。不同治疗方法和不同肿瘤类型上治疗前动态心电图各项指标比较差异无统计学意义（P ＞0．05）；治疗后各项指标比较差异也无统计学意义（P ＞0．05）。结论：调强放射治疗后胸部肿瘤患者动态心电图改变多在早期出现，且为可逆性。调强放射治疗精确性保证了不同类型胸部肿瘤放疗后动态心电图改变无显著差异性。
목적：탐토흉부종류환자재불동시간단、불동류형종류、불동치료방법하조강방료동태심전도변화정황。방법：선취2010년4월－2013년4월95례흉부종류환자위연구대상，안조종류류형분성폐암조35례，유선암조29례，식관암조31례；안조치료방법분성단순방료조26례，동보방화조34례，서관방화조35례，분별재치료전、치료후화치료결속6개월후관찰동태심전도변화정황。결과：치료후화치료전재우발실（방）성심률실상、ST －T 단개변동태심전도이상발생솔상비교차이유통계학의의（P ＜0．05），이치료결속6개월후화치료전재우발실（방）성심률실상、ST －T 단개변동태심전도이상발생솔비교차이무통계학의의（P＞0．05）。불동치료방법화불동종류류형상치료전동태심전도각항지표비교차이무통계학의의（P ＞0．05）；치료후각항지표비교차이야무통계학의의（P ＞0．05）。결론：조강방사치료후흉부종류환자동태심전도개변다재조기출현，차위가역성。조강방사치료정학성보증료불동류형흉부종류방료후동태심전도개변무현저차이성。
Objective:To investigate breast cancer patients at different time periods,different types of cancer,dif-ferent treatments of radiotherapy Holter strong downward changes.Methods:All 95 breast cancer patients according to tumor type were 35 cases of lung cancer,breast cancer group,29 cases,31 cases of esophageal cancer.Divided into groups according to treatment with radiotherapy alone 26,synchronous chemoradiotherapy group 34 cases,35 cases of sequential chemoradiotherapy group.Before and after treatment and six months after the end of treatment was observed on dynamic ECG changes.Results:Before treatment,and treatment in occasional room(room)arrhythmia,incidence of abnormalities ST -T segment changes on Holter difference was statistically significant(P <0.05),but before and after treatment in episodic treatment room(room)arrhythmia,ST -T segment changes in the incidence of abnormal Holter was no significant difference(P >0.05).The former Holter indexes difference was not statistically significant (P >0.05)after treatment in different treatment methods and different tumor types.Each index difference also was not statistically significant after treatment(P >0.05).Conclusion:IMRT breast cancer patients after treatment Holter change much in the early stage,and is reversible.IMRT guarantee the accuracy of the different types of breast cancer radiotherapy after changing Holter no significant difference.