CAJ | 학술논문

近年来，食品安全问题成为各国关注的焦点问题。食品安全风险监测工作正面临巨大的挑战。代谢组学技术作为一个新兴的重要研究技术，在食品质量与安全、临床诊断和环境科学等领域广泛应用，食品及其危害物残留对机体的影响等食品安全问题可用代谢组学的技术进行全面分析。随着仪器手段的创新以及化学计量学的发展，代谢组学将与基因组学、蛋白质组学和转录组学的数据库相互衔接，推动系统生物学的发展，为食品质量与安全研究提供一个高通量、高灵敏度、高准确性平台。本文主要介绍代谢组学的研究方法及其在食品安全风险监测与评估方面的应用，以推动我国在快速检测检验方面的技术进步和突破，从而达到保障食品安全的目的。
근년래，식품안전문제성위각국관주적초점문제。식품안전풍험감측공작정면림거대적도전。대사조학기술작위일개신흥적중요연구기술，재식품질량여안전、림상진단화배경과학등영역엄범응용，식품급기위해물잔류대궤체적영향등식품안전문제가용대사조학적기술진행전면분석。수착의기수단적창신이급화학계량학적발전，대사조학장여기인조학、단백질조학화전록조학적수거고상호함접，추동계통생물학적발전，위식품질량여안전연구제공일개고통량、고령민도、고준학성평태。본문주요개소대사조학적연구방법급기재식품안전풍험감측여평고방면적응용，이추동아국재쾌속검측검험방면적기술진보화돌파，종이체도보장식품안전적목적。
Food safety has become the focus of many countries in recent years. Food safety risk monitoring is facing huge challenges. Metabolomics is an emerged important research tool besides genomics and proteomics. Recently, metabolomics has been widely used in many fields, including food quality and safety, clinical diagnosis, and environmental science. Moreover, it can be used to analyze the influence of food and its hazard residues on organism. With the development of instruments and stoichiometry, metabolomics will combine with database of genomics and proteomics to promote the growth of system biology for providing a platform with high throughput, sensitivity and precision. The paper summarized metabolomics methods and its potential applications in food safety risk monitoring and assessment in order to improve the development of rapid detection technology in China and ensure food safety.