CAJ | 학술논문

近些年来海洋污染越来越严重，赤潮频发直接导致海洋生物毒素对贝类产品大面积污染，这不仅直接影响海洋产品的品质和食用安全，更加阻碍了海洋养殖业的健康发展，对食品安全造成极大威胁。为了解决海洋产品的食品安全问题，保障人们生命健康，对海洋生物毒素分析检测的研究已越来越多。本文综述了腹泻性贝类毒素的主要特征、主要毒素成分及毒理效应，并对小鼠生物测试法、酶联免疫检测法、胶束电动色谱法、酶活力抑制法、毛细管电泳法、高效液相色谱以及高效液相色谱-质谱法等常用的检测方法作以综合性评价，并对其研究进展加以介绍。
근사년래해양오염월래월엄중，적조빈발직접도치해양생물독소대패류산품대면적오염，저불부직접영향해양산품적품질화식용안전，경가조애료해양양식업적건강발전，대식품안전조성겁대위협。위료해결해양산품적식품안전문제，보장인문생명건강，대해양생물독소분석검측적연구이월래월다。본문종술료복사성패류독소적주요특정、주요독소성분급독리효응，병대소서생물측시법、매련면역검측법、효속전동색보법、매활력억제법、모세관전영법、고효액상색보이급고효액상색보-질보법등상용적검측방법작이종합성평개，병대기연구진전가이개소。
In recent years, marine pollution has become more and more serious. The frequent occurrence of red tides directly leads to marine toxins pollution on shellfish, which not only directly affect the quality and safety of marine products, but also hinder the healthy development of the marine aquaculture industry. In order to solve the safety problem of marine products and protect people's life and health, the analysis and detection of marine biological toxins has been more and more concerned. The main characteristics, toxin components and toxicological effect of the diarrhea shellfish poisoning were reviewed in this paper. The detection methods including mouse bioassay, enzyme-linked immunosorbent assay (ELISA), molecular biological detection, micellar electrokinetic chromatography, enzyme inhibition methods, capillary electrophoresis, high performance liquid chromatography(HPLC), high performance liquid chromatography-mass spectrometry (HPLC-MS) were used to evaluate the comprehensive evaluation, and were also summarized in this paper.