CAJ | 학술논문

目的：明确玛咖粉对小鼠免疫功能的调节作用。方法40只小鼠进行玛咖粉抗体生成细胞测定、对小鼠 HC50的影响、碳廓清能力以及鸡红细胞吞噬率及吞噬指数的影响实验。实验设4组,灌胃的玛咔粉分别为0、0.3、0.6、0.9 g/(kg·bw),连续灌胃30 d后测定各项指标。结果0.3 g/(kg·bw)及0.9 g/(kg·bw)组玛咔粉可以显著促进小鼠B细胞分泌抗体的能力(P<0.05),0.9 g/(kg·bw)组玛咔粉具有显著增加小鼠半数溶血值(HC50)(P<0.01),0.6 g/(kg·bw)及0.9 g/(kg·bw)组可以显著提高小鼠单核-巨噬细胞碳廓清能力(P<0.05),0.9 g/(kg?bw)组可以显著提高小鼠腹腔巨噬细胞鸡红细胞吞噬率及吞噬指数(P<0.05)。结论玛咔粉可以增强小鼠体液免疫功能和单核-巨噬细胞功能的作用。
목적：명학마가분대소서면역공능적조절작용。방법40지소서진행마가분항체생성세포측정、대소서 HC50적영향、탄곽청능력이급계홍세포탄서솔급탄서지수적영향실험。실험설4조,관위적마잡분분별위0、0.3、0.6、0.9 g/(kg·bw),련속관위30 d후측정각항지표。결과0.3 g/(kg·bw)급0.9 g/(kg·bw)조마잡분가이현저촉진소서B세포분비항체적능력(P<0.05),0.9 g/(kg·bw)조마잡분구유현저증가소서반수용혈치(HC50)(P<0.01),0.6 g/(kg·bw)급0.9 g/(kg·bw)조가이현저제고소서단핵-거서세포탄곽청능력(P<0.05),0.9 g/(kg?bw)조가이현저제고소서복강거서세포계홍세포탄서솔급탄서지수(P<0.05)。결론마잡분가이증강소서체액면역공능화단핵-거서세포공능적작용。
Objective To evaluate the regulation effects of powderedLepidium meyenii(Maca) on immune function in mice.MethodsForty mice were used to conduct antibody-producing cell of spleen, total hemolytic complement assay (HC50 assay), clearance of carbon particles, and chicken red blood cell phagocytic rate and phagocytic index assay. The 40 mice were randomly divided into 4 groups (n=10): 0, 0.3, 0.6 and 0.9 g/(kg.bw) powdered Maca were orally administered once daily for 30 d.ResultsIn comparison with the control group, 0.3 g/(kg.bw) and 0.9 g/(kg.bw) powdered Maca significantly increased the ability of mice B cells secreting antibodies (P<0.05), 0.9 g/(kg.bw) powdered Maca significantly increased HC50 value (P<0.01), 0.6g/(kg.bw) and 0.9 g/(kg.bw) powdered Maca significantly increased the ability of carbon particles clearance by mice macrophages (P<0.05), and 0.9 g/(kg.bw) powdered Maca significantly enhanced the phagocytic rate and phagocytic index of chicken red blood cells in mouse peritoneal macrophages (P<0.05).Conclusion Powdered Maca can enhance the function of humoral immune and monocyte macrophage in mice.