齐齐哈尔医学院学报
齊齊哈爾醫學院學報
제제합이의학원학보
Journal of Qiqihar University of Medicine
2015年
29期
4409-4411
,共3页
血管性痴呆%H型高血压%依那普利叶酸片%依那普利片
血管性癡呆%H型高血壓%依那普利葉痠片%依那普利片
혈관성치태%H형고혈압%의나보리협산편%의나보리편
Vascular dementia%H type hypertension%Enalapril folic acid tablets%Enalapril
目的：探索研究应用依那普利叶酸片以及依那普利片针对血管性痴呆伴H型高血压患者进行治疗的作用和效果。方法选择我院收治的血管性痴呆伴H型高血压的患者作为研究对象并进行分组治疗，研究组均予以依那普利叶酸片，对照组均予以依那普利片，均持续治疗6个月。将两组患者治疗前后的血压、血同型半胱氨酸以及MMSE评分变化情况进行对比。结果两组患者经对应方法治疗后，平均动脉血压均得到有效下降（P＜0．05），而组间比较差异不具有显著性（P＞0．05）。治疗后，Hcy水平均显著降低，研究组显著低于对照组（P＜0．05）；MMSE评分均显著增高，研究组显著高于对照组（P＜0．05）。结论应用依那普利叶酸片对血管性痴呆伴H型高血压患者进行治疗，可以产生显著的临床效果，能够有效降低Hcy水平，同时有效改善MMSE评分，安全性高，具有极大的推广应用价值。
目的：探索研究應用依那普利葉痠片以及依那普利片針對血管性癡呆伴H型高血壓患者進行治療的作用和效果。方法選擇我院收治的血管性癡呆伴H型高血壓的患者作為研究對象併進行分組治療，研究組均予以依那普利葉痠片，對照組均予以依那普利片，均持續治療6箇月。將兩組患者治療前後的血壓、血同型半胱氨痠以及MMSE評分變化情況進行對比。結果兩組患者經對應方法治療後，平均動脈血壓均得到有效下降（P＜0．05），而組間比較差異不具有顯著性（P＞0．05）。治療後，Hcy水平均顯著降低，研究組顯著低于對照組（P＜0．05）；MMSE評分均顯著增高，研究組顯著高于對照組（P＜0．05）。結論應用依那普利葉痠片對血管性癡呆伴H型高血壓患者進行治療，可以產生顯著的臨床效果，能夠有效降低Hcy水平，同時有效改善MMSE評分，安全性高，具有極大的推廣應用價值。
목적：탐색연구응용의나보리협산편이급의나보리편침대혈관성치태반H형고혈압환자진행치료적작용화효과。방법선택아원수치적혈관성치태반H형고혈압적환자작위연구대상병진행분조치료，연구조균여이의나보리협산편，대조조균여이의나보리편，균지속치료6개월。장량조환자치료전후적혈압、혈동형반광안산이급MMSE평분변화정황진행대비。결과량조환자경대응방법치료후，평균동맥혈압균득도유효하강（P＜0．05），이조간비교차이불구유현저성（P＞0．05）。치료후，Hcy수평균현저강저，연구조현저저우대조조（P＜0．05）；MMSE평분균현저증고，연구조현저고우대조조（P＜0．05）。결론응용의나보리협산편대혈관성치태반H형고혈압환자진행치료，가이산생현저적림상효과，능구유효강저Hcy수평，동시유효개선MMSE평분，안전성고，구유겁대적추엄응용개치。
Objective To explore the application effect of enalapril and enalapril folic acid tablets in the treatment of vascular dementia combined with H type hypertension .Methods Vascular dementia combined with H type hypertension patients in our hospital were chose as the research object and were divided into two groups , study group were treated with enalapril folic acid tablets , control group were treated with enalapril , lasted for 6 months.Comparing the blood pressure and blood homocysteine and MMSE score changes before and after treatment of the two groups .Results After corresponding treatment , mean arterial blood pressure of the two groups were effectively decreased (P<0.05), however, the difference between groups was not significant (P>0.05).After treatment, the levels of Hcy were significantly decreased , and this in study group was significantly lower than the control group (P <0.05).The MMSE score increased significantly, and the study group was significantly higher than the control group (P <0.05).Conclusions The application of enalapril folic acid tablets on vascular dementia combined with H type hypertension have significant clinical effect , can reduce the Hcy level and effectively improve the score of MMSE , with high safety , it has great popularization and application value.
