中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
Chinese Journal of ocular trauma and occupational eye disease
2015年
10期
790-792
,共3页
干眼%白内障%超声乳化%小牛血去蛋白提取物眼用凝胶
榦眼%白內障%超聲乳化%小牛血去蛋白提取物眼用凝膠
간안%백내장%초성유화%소우혈거단백제취물안용응효
Dry eye%Cataract%Phacoemulsification%Deproteinised calf blood extract eye gel
目的：观察小牛血去蛋白提取物眼用凝胶预防白内障超声乳化术后干眼的效果。方法选取本院白内障超声乳化手术58例(69眼),男28例(33眼),女30例(36眼),年龄52~79岁。按照随机原则将患者分为观察组(应用小牛血去蛋白凝胶滴眼,35眼)和对照组(34眼),两组患者术前均给予妥布霉素滴眼液滴眼3 d,术后均给予妥布霉素地塞米松滴眼液滴眼1个月；观察组于术后1 d起加用小牛血去蛋白提取物眼用凝胶滴眼,4次/d ,持续1月。结果两组治疗后相比,观察组基础泪液分泌试验结果优于对照组；观察组泪膜破裂时间长于对照组；观察组角膜荧光染色评分上皮修复优于对照组,差异均有统计学意义(P<0.05)。结论小牛血去蛋白提取物能够在白内障手术后早期发挥促角膜上皮再生及角膜创伤愈合的作用,改善干眼的症状,稳定泪膜。
目的：觀察小牛血去蛋白提取物眼用凝膠預防白內障超聲乳化術後榦眼的效果。方法選取本院白內障超聲乳化手術58例(69眼),男28例(33眼),女30例(36眼),年齡52~79歲。按照隨機原則將患者分為觀察組(應用小牛血去蛋白凝膠滴眼,35眼)和對照組(34眼),兩組患者術前均給予妥佈黴素滴眼液滴眼3 d,術後均給予妥佈黴素地塞米鬆滴眼液滴眼1箇月；觀察組于術後1 d起加用小牛血去蛋白提取物眼用凝膠滴眼,4次/d ,持續1月。結果兩組治療後相比,觀察組基礎淚液分泌試驗結果優于對照組；觀察組淚膜破裂時間長于對照組；觀察組角膜熒光染色評分上皮脩複優于對照組,差異均有統計學意義(P<0.05)。結論小牛血去蛋白提取物能夠在白內障手術後早期髮揮促角膜上皮再生及角膜創傷愈閤的作用,改善榦眼的癥狀,穩定淚膜。
목적：관찰소우혈거단백제취물안용응효예방백내장초성유화술후간안적효과。방법선취본원백내장초성유화수술58례(69안),남28례(33안),녀30례(36안),년령52~79세。안조수궤원칙장환자분위관찰조(응용소우혈거단백응효적안,35안)화대조조(34안),량조환자술전균급여타포매소적안액적안3 d,술후균급여타포매소지새미송적안액적안1개월；관찰조우술후1 d기가용소우혈거단백제취물안용응효적안,4차/d ,지속1월。결과량조치료후상비,관찰조기출루액분비시험결과우우대조조；관찰조루막파렬시간장우대조조；관찰조각막형광염색평분상피수복우우대조조,차이균유통계학의의(P<0.05)。결론소우혈거단백제취물능구재백내장수술후조기발휘촉각막상피재생급각막창상유합적작용,개선간안적증상,은정루막。
Objective To observe the efficacy of deproteinised calf blood extract eye gel for preventing dry eye after phacoemulsification. Methods Sixty-nine eyes of 58 patients who received phacoemulsification were collected, including 28 male ( 33 eyes ) and 30 female ( 36 eyes ) . They were randomly divided into treatment group (35 eyes) and control group (34 eyes). The age of the patients was from 52 to 79 years. All patients were given tobramycin eye drops for 3 days prior to the surgery and tobramycin-dexamethasone eye drops for 1 month after the surgery. The patients in treatment group were given additionally deproteinised calf blood extract eye gel four times a day since the first day after the surgery for 1 month. Results The Schirmer test results in the treatment group was better than that in control group, and the difference was statistically significant (P<0. 01). The breakup time of tear film (BUT) in the treatment group was significantly longer than that in control group. The corneal epithelium repair scoring by fluorescein staining ( FL) in treatment group was better than that in control group, and the difference was statistically significant(P <0. 05). Conclusion Deproteinised calf blood extract eye gel can promote corneal epithelial regeneration and corneal wound healing in early stage after cataract surgery, with improving of dry eye symptoms, and stabilization of the tear film.
