国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
International Journal of Pediatrics
2015年
5期
599-602
,共4页
特应性皮炎%自然进程
特應性皮炎%自然進程
특응성피염%자연진정
Atopic dermatitis%Natural course
特应性皮炎的自然进程一直都是医师与患者所关心的课题.特应性皮炎的发病机制复杂,涉及遗传、免疫、环境及生活方式等多种因素,与皮肤屏障受损和免疫系统功能失调有关.特应性皮炎在发病年龄、病程、加重及缓解因素和对治疗的反应上都有个体差异.近年来,随着遗传学研究及临床大量回顾性研究进展,对特应性皮炎自然进程的认识更为全面,这有助于个体化治疗方案的制定与疗效评价.
特應性皮炎的自然進程一直都是醫師與患者所關心的課題.特應性皮炎的髮病機製複雜,涉及遺傳、免疫、環境及生活方式等多種因素,與皮膚屏障受損和免疫繫統功能失調有關.特應性皮炎在髮病年齡、病程、加重及緩解因素和對治療的反應上都有箇體差異.近年來,隨著遺傳學研究及臨床大量迴顧性研究進展,對特應性皮炎自然進程的認識更為全麵,這有助于箇體化治療方案的製定與療效評價.
특응성피염적자연진정일직도시의사여환자소관심적과제.특응성피염적발병궤제복잡,섭급유전、면역、배경급생활방식등다충인소,여피부병장수손화면역계통공능실조유관.특응성피염재발병년령、병정、가중급완해인소화대치료적반응상도유개체차이.근년래,수착유전학연구급림상대량회고성연구진전,대특응성피염자연진정적인식경위전면,저유조우개체화치료방안적제정여료효평개.
The natural course of atopic dermatitis (AD) has been a key subject with major concerns of physicians and patients.Tne pathogenesis of AD is complicated, which is associated with genetic, immunological,environmental and lifestyle factors, resulting in skin barrier impairment and immune system dysfunction.Therefore, there are individual differences in the age of onset, duration, aggravation, prognostic factors for remission and response to treatment.In recent years, with evidence of genetic research and a large amount of clinical retrospective studies,we have a more comprehensive understanding of the natural course of AD,which will help develop individualized treatment and evaluation strategies.
