现代肿瘤医学
現代腫瘤醫學
현대종류의학
Journal of Modern Oncology
2015年
21期
3128-3131
,共4页
韩晓鹏%许威%于建平%刘宏斌%苏琳
韓曉鵬%許威%于建平%劉宏斌%囌琳
한효붕%허위%우건평%류굉빈%소림
腹腔镜%胃癌%无瘤操作
腹腔鏡%胃癌%無瘤操作
복강경%위암%무류조작
laparoscopic%gastric cancer%disease-free
目的:探讨应用无瘤技术后腹腔镜下胃癌根治术对肿瘤脱落细胞的影响,评价其安全性及可行性。方法:收集65例行腹腔镜胃癌手术患者切除前后腹腔冲洗液,细胞学检测腹腔游离癌细胞,并以流式细胞学(FCM)方法检测腹腔冲洗液癌胚抗原(CEA)及基质金属蛋白酶-7(MMP-7),对比术前、术后检出率。结果:65例规范无瘤操作的腹腔镜胃癌根治术患者腹腔游离癌细胞术前、术后检出率分别为6.15%(4/65)和9.23%(6/65),CEA检测阳性率术前、术后分别为46.2%(30/65)和52.3%(34/65),MMP-7检测阳性率术前、术后分别为56.9%(37/65)和64.6%(42/65),术后较手术前高,但两者差异无统计学意义( P﹥0.05)。结论:严格遵守无瘤操作规程的腹腔镜胃癌根治术,不增加癌细胞的脱落,也不增加腹腔种植转移几率,是安全可行的。
目的:探討應用無瘤技術後腹腔鏡下胃癌根治術對腫瘤脫落細胞的影響,評價其安全性及可行性。方法:收集65例行腹腔鏡胃癌手術患者切除前後腹腔遲洗液,細胞學檢測腹腔遊離癌細胞,併以流式細胞學(FCM)方法檢測腹腔遲洗液癌胚抗原(CEA)及基質金屬蛋白酶-7(MMP-7),對比術前、術後檢齣率。結果:65例規範無瘤操作的腹腔鏡胃癌根治術患者腹腔遊離癌細胞術前、術後檢齣率分彆為6.15%(4/65)和9.23%(6/65),CEA檢測暘性率術前、術後分彆為46.2%(30/65)和52.3%(34/65),MMP-7檢測暘性率術前、術後分彆為56.9%(37/65)和64.6%(42/65),術後較手術前高,但兩者差異無統計學意義( P﹥0.05)。結論:嚴格遵守無瘤操作規程的腹腔鏡胃癌根治術,不增加癌細胞的脫落,也不增加腹腔種植轉移幾率,是安全可行的。
목적:탐토응용무류기술후복강경하위암근치술대종류탈락세포적영향,평개기안전성급가행성。방법:수집65례행복강경위암수술환자절제전후복강충세액,세포학검측복강유리암세포,병이류식세포학(FCM)방법검측복강충세액암배항원(CEA)급기질금속단백매-7(MMP-7),대비술전、술후검출솔。결과:65례규범무류조작적복강경위암근치술환자복강유리암세포술전、술후검출솔분별위6.15%(4/65)화9.23%(6/65),CEA검측양성솔술전、술후분별위46.2%(30/65)화52.3%(34/65),MMP-7검측양성솔술전、술후분별위56.9%(37/65)화64.6%(42/65),술후교수술전고,단량자차이무통계학의의( P﹥0.05)。결론:엄격준수무류조작규정적복강경위암근치술,불증가암세포적탈락,야불증가복강충식전이궤솔,시안전가행적。
Objective:To explore the application of laparoscopic gastric cancer after radical disease-free technol-ogy,evaluate the safety and feasibility. Methods:Collect 65 patients with gastric cancer underwent laparoscopic surgi-cal resection in before and after abdominal rinses,cytological examination intraperitoneal free cancer cells,fluid cytol-ogy(FCM)method in detecting celiac rinses carcinoembryonic antigen(CEA)and matrix metalloproteinases -7 (MMP-7),compare the preoperative and postoperative detection rate. Results:In 65 cases of specification disease-free laparoscopic operation intraperitoneal free cancer cells in patients with preoperative and postoperative gastric cancer radical detection rate was 6. 15%(4/65)and 9. 23%(6/65),CEA detection rate of preoperative and postop-erative were 46. 2%(30/65)and 52. 3%(34/65),MMP-7 detection rate of preoperative and postoperative were 56. 9%(37/65)and 64. 6%(42/65),higher than before the operation,but there was no statistically significant difference between the two(P ﹥0. 05). Conclusion:Strictly operation rules on disease -free,laparoscopic gastric cancer radical shedding not increase cancer cells,nor increase abdominal planting transfer probability,is safe and fea-sible.