CAJ | 학술논문

目的：探讨胃肝样腺癌患者的治疗以及预后，同时分析血清甲胎蛋白在诊断胃肝样腺癌及判断预后中的临床意义。方法：分析15例手术病理证实为胃肝样腺癌患者的临床资料。结果：15例患者，生存时间3.1~24个月，平均10.52个月，术前血清AFP浓度范围为25.23~13500μg/L。结论：胃肝样腺癌AFP 水平波动范围大，血清AFP 升高是胃肝样腺癌重要的临床病理特点，在胃肝样腺癌诊治中具有重要价值，可作为早期诊断的条件之一，同时可以用于监测肿瘤复发与转移。胃肝样腺癌预后极差，合并肝转移或者门静脉癌栓患者建议避免手术治疗。
목적：탐토위간양선암환자적치료이급예후，동시분석혈청갑태단백재진단위간양선암급판단예후중적림상의의。방법：분석15례수술병리증실위위간양선암환자적림상자료。결과：15례환자，생존시간3.1~24개월，평균10.52개월，술전혈청AFP농도범위위25.23~13500μg/L。결론：위간양선암AFP 수평파동범위대，혈청AFP 승고시위간양선암중요적림상병리특점，재위간양선암진치중구유중요개치，가작위조기진단적조건지일，동시가이용우감측종류복발여전이。위간양선암예후겁차，합병간전이혹자문정맥암전환자건의피면수술치료。
Objective:To investigate the treatment and prognosis of the hepatoid adenocarcinoma of the stomach ( HAS),and analyze serum alpha fetoprotein( AFP)clinical significance of HAS in diagnosis and prognosis. Meth-ods:Collected 15 cases of pathologically confirmed HAS with positive AFP. Results:The survival time of all 1 5 pa-tients was 3 . 1 ~2 4 months ,the average was 1 0 . 5 2 months . Serum AFP concentrations ranged from 2 5 . 2 3 to 13 500μg/L. Conclusion:AFP level of HAS fluctuate widely. And elevate AFP is an important clinical and pathologi-cal feature of HAS. It is very useful for the diagnosis and treatment of HAS. Its useful for the early diagnosis and moni-tor of recurrence and metastasis of tumor. The prognosis of HAS is very poor,especially for patients with liver metasta-sis or portal vein tumor thrombus. We should avoid operations for metastasis cases.