CAJ | 학술논문

目的：分析维汉两族2型DM住院患者慢性微血管并发症的构成比及相关危险因素。方法收集2011年9月～2014年10月在我科住院的500例2型DM患者进行回顾性调查。入组病例按维汉分组，维族患者300例，汉族患者200例，分别统计其糖尿病肾病（DNP）、糖尿病视网膜病变（DRP）、糖尿病周围神经病变（DUP）的构成比，用logistic多元回归分析维汉两族2型DM患者各类慢性微血管并发症的相关危险因素。结果在住院的2型DM患者中，汉族DNP患病率为35.4%，维族DNP的患病率为32.4%；汉族DRP的患病率为17.5%，维族DRP的患病率为19.8%；汉族DUP的患病率为29.2%，维族DUP的患病率为30.4%。结论 Logistic回归结果显示，伴高血压病、高胆固醇血症（TC）、糖尿病病程是汉族患者DNP的独立危险因素，较高的空腹血糖（FPG）、糖化血红蛋白（HbA1c）水平是维族患者DNP的独立危险因素；糖尿病病程是维族DRP的独立危险因素；伴高血压病、糖尿病病程、较高的HbA1c是汉族DUP的独立危险因素，增龄、糖尿病病程、较高的低密度脂蛋（LDL-C）、FPG、HbA1c是维族DUP的独立危险因素。
목적：분석유한량족2형DM주원환자만성미혈관병발증적구성비급상관위험인소。방법수집2011년9월～2014년10월재아과주원적500례2형DM환자진행회고성조사。입조병례안유한분조，유족환자300례，한족환자200례，분별통계기당뇨병신병（DNP）、당뇨병시망막병변（DRP）、당뇨병주위신경병변（DUP）적구성비，용logistic다원회귀분석유한량족2형DM환자각류만성미혈관병발증적상관위험인소。결과재주원적2형DM환자중，한족DNP환병솔위35.4%，유족DNP적환병솔위32.4%；한족DRP적환병솔위17.5%，유족DRP적환병솔위19.8%；한족DUP적환병솔위29.2%，유족DUP적환병솔위30.4%。결론 Logistic회귀결과현시，반고혈압병、고담고순혈증（TC）、당뇨병병정시한족환자DNP적독립위험인소，교고적공복혈당（FPG）、당화혈홍단백（HbA1c）수평시유족환자DNP적독립위험인소；당뇨병병정시유족DRP적독립위험인소；반고혈압병、당뇨병병정、교고적HbA1c시한족DUP적독립위험인소，증령、당뇨병병정、교고적저밀도지단（LDL-C）、FPG、HbA1c시유족DUP적독립위험인소。
Objective To analyze the proportion and related risk factors of chronic microvascular complications among Xinjiang Uighurs and the Han nationality hospitalized patients who suffered from type 2 diabetes mellitus. Methods All data about 500 patients with type 2 diabetes mellitus who were ever treated in the Endocrinology department in our hospital from September 2011 to October 2014 were collected. And then all the data were divided into two groups according to the nationalities of the patients, that is, 300 patients in Uygur group and 200 patients in Han group. Then the constituent ratio of the diabetic nephropathy (DNP), diabetic retinopathy (DRP), the composition of diabetic peripheral neuropathy (DUP) were calculated by Logistic multivariate regression. The correlation and related risk factors of chronic microvascular complications in all those hospitalized patients with different nationalities who suffered from type 2 diabetes mellitus were analyzed. Results Among hospitalized patients illed with type 2 diabetes, the prevalence race of DNP in Han patients was 35.4%compared with 32.4%in Uygur patients. The prevalence race of DRP in Han patients was 17.5%, compared by 19.8%in Uygur patients. The prevalence race of DUP in Han patients was 29.2%while being 30.4%in Uygur patients. Conclusion The results showed that hypertension, hypercholesterolemia, and diabetes duration time were independent risk factors for the development of DNP in the Han patients .The higher fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) levels were independent risk factors for the development of DNP in Uygur patients .The diabetes duration time was Independent risk factors for DRP in Uygur patients. Hypertension, diabetes duration and higher HbA1c were independent risk factors for DUP in the Han patients. The age, duration time of diabetes, higher LDL eggs (LDL-C), FPG and HbA1c were independent risk factors for DUP in Uygur patients.