中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2015年
8期
884-886
,共3页
舒芬太尼%二异丙酚%胃镜检查
舒芬太尼%二異丙酚%胃鏡檢查
서분태니%이이병분%위경검사
Sufentanil%Propofol%Gastroscopy
目的 探讨舒芬太尼复合丙泊酚在胃镜检查中的镇静效果和安全性. 方法 选择ASA Ⅰ-Ⅱ级270例胃镜检查患者,随机分成3组,即丙泊酚组、芬太尼加丙泊酚组和舒芬太尼加丙泊酚组,每组90例.分别记录胃镜检查前、镜检时及镜检后5 min的心率、平均动脉压、血氧饱和度.记录患者意识恢复时间、定向力恢复时间、胃镜操作时间以及丙泊酚的用量. 结果 3组患者术中心率、平均动脉压、血氧饱和度与术前或术后相比均降低(P<0.05),各组之间心率、平均动脉压、血氧饱和度比较差异均有统计学意义(均P<0.05).意识恢复时间、定向力恢复时间丙泊酚组、芬太尼加丙泊酚组较舒芬太尼加丙泊酚组相比延长(均P<0.05),芬太尼加丙泊酚组、舒芬太尼加丙泊酚组之间差异亦有统计学意义(均P<0.05).丙泊酚组比芬尼民加丙泊酚组、较舒芬太尼加丙泊酚组丙泊酚用量增加(P<0.05). 结论 舒芬太尼和丙泊酚联合应用起效时间快,丙泊酚用量明显减少,不良反应少,且镇静效果增强,患者满意度高.
目的 探討舒芬太尼複閤丙泊酚在胃鏡檢查中的鎮靜效果和安全性. 方法 選擇ASA Ⅰ-Ⅱ級270例胃鏡檢查患者,隨機分成3組,即丙泊酚組、芬太尼加丙泊酚組和舒芬太尼加丙泊酚組,每組90例.分彆記錄胃鏡檢查前、鏡檢時及鏡檢後5 min的心率、平均動脈壓、血氧飽和度.記錄患者意識恢複時間、定嚮力恢複時間、胃鏡操作時間以及丙泊酚的用量. 結果 3組患者術中心率、平均動脈壓、血氧飽和度與術前或術後相比均降低(P<0.05),各組之間心率、平均動脈壓、血氧飽和度比較差異均有統計學意義(均P<0.05).意識恢複時間、定嚮力恢複時間丙泊酚組、芬太尼加丙泊酚組較舒芬太尼加丙泊酚組相比延長(均P<0.05),芬太尼加丙泊酚組、舒芬太尼加丙泊酚組之間差異亦有統計學意義(均P<0.05).丙泊酚組比芬尼民加丙泊酚組、較舒芬太尼加丙泊酚組丙泊酚用量增加(P<0.05). 結論 舒芬太尼和丙泊酚聯閤應用起效時間快,丙泊酚用量明顯減少,不良反應少,且鎮靜效果增彊,患者滿意度高.
목적 탐토서분태니복합병박분재위경검사중적진정효과화안전성. 방법 선택ASA Ⅰ-Ⅱ급270례위경검사환자,수궤분성3조,즉병박분조、분태니가병박분조화서분태니가병박분조,매조90례.분별기록위경검사전、경검시급경검후5 min적심솔、평균동맥압、혈양포화도.기록환자의식회복시간、정향력회복시간、위경조작시간이급병박분적용량. 결과 3조환자술중심솔、평균동맥압、혈양포화도여술전혹술후상비균강저(P<0.05),각조지간심솔、평균동맥압、혈양포화도비교차이균유통계학의의(균P<0.05).의식회복시간、정향력회복시간병박분조、분태니가병박분조교서분태니가병박분조상비연장(균P<0.05),분태니가병박분조、서분태니가병박분조지간차이역유통계학의의(균P<0.05).병박분조비분니민가병박분조、교서분태니가병박분조병박분용량증가(P<0.05). 결론 서분태니화병박분연합응용기효시간쾌,병박분용량명현감소,불량반응소,차진정효과증강,환자만의도고.
Objective To investigate the Sedative effect and safety of intravenous Sufentanil combined with Propofol in painless gastroscopy.Methods 270 patients with ASA Ⅰ-Ⅱ were randomly divided into three groups:Group A (the Propofol group),Group B (the Fentanyl combined with Propofol group) and Group C (the Sufentanil combined with Propofol group).HR,MAP and SpO2 were monitored at three different time points:before placement of the gastroscope,during and 5 minutes after gastroscopy.The time required for consciousness recovery,the time required for regaining orientation,the operating time for gastroscopy and the dosage of Propofol were recorded.Results HR,MAP and SpO2 were obviously lower during operation than before or after operation in each group (P<0.05) and were significant different among the groups (P< 0.05).The times required for consciousness recovery and for regaining orientation,respectively,were significantly longer in Group A than in Group B or C,and there was a significantly difference between Group B and Group C (P<0.05).The total dose of Propofol in Group A was significantly larger than that in Group B or C (P<0.05).Conclusions Compared with Propofol alone or Fentanyl combined with Propofol,Sufentanil can be used in combination with lower does of Propofol in painless gastroscopy to produce rapid and effective Sedation,with fewer side effects and higher patient satisfaction.