医药前沿
醫藥前沿
의약전연
Yiayao Qianyan
2015年
26期
24-25
,共2页
丙型肝炎病毒基因型%丙氨酸氨基转移酶%天门冬氨酸氨基转移酶%肝纤维化
丙型肝炎病毒基因型%丙氨痠氨基轉移酶%天門鼕氨痠氨基轉移酶%肝纖維化
병형간염병독기인형%병안산안기전이매%천문동안산안기전이매%간섬유화
Hepatitis c virus genotype%Alanine aminotransferase%Aspartate amino transferase%Liver fibrosis
目的:探讨丙型肝炎病毒(HCV)基因型与肝脏损伤严重程度之间的关系.方法:采用PCR荧光探针法进行基因分型检测,并检测患者未治疗前丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、清蛋白(ALB)、血红蛋白(Hb)、血小板计数(PLT)水平.结果:2a型患者ALT和AST明显高于1b型患者(P<0.05),而ALB、Hb、PLT、APQI水平1b型和2a型两者间无显著性差异(P>0.05).结论:HCV 2a型患者肝脏急性损伤程度较1b型严重,但肝脏纤维化严重程度两型未见差异.
目的:探討丙型肝炎病毒(HCV)基因型與肝髒損傷嚴重程度之間的關繫.方法:採用PCR熒光探針法進行基因分型檢測,併檢測患者未治療前丙氨痠氨基轉移酶(ALT)、天門鼕氨痠氨基轉移酶(AST)、清蛋白(ALB)、血紅蛋白(Hb)、血小闆計數(PLT)水平.結果:2a型患者ALT和AST明顯高于1b型患者(P<0.05),而ALB、Hb、PLT、APQI水平1b型和2a型兩者間無顯著性差異(P>0.05).結論:HCV 2a型患者肝髒急性損傷程度較1b型嚴重,但肝髒纖維化嚴重程度兩型未見差異.
목적:탐토병형간염병독(HCV)기인형여간장손상엄중정도지간적관계.방법:채용PCR형광탐침법진행기인분형검측,병검측환자미치료전병안산안기전이매(ALT)、천문동안산안기전이매(AST)、청단백(ALB)、혈홍단백(Hb)、혈소판계수(PLT)수평.결과:2a형환자ALT화AST명현고우1b형환자(P<0.05),이ALB、Hb、PLT、APQI수평1b형화2a형량자간무현저성차이(P>0.05).결론:HCV 2a형환자간장급성손상정도교1b형엄중,단간장섬유화엄중정도량형미견차이.
Objective Hepatitis c virus (HCV) genotypes and the relationship between the severity of liver damage.Methods By PCR fluorescence probe method is used to detect the genotyping, patients before treatment and testing alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin (propagated), hemoglobin (Hb), platelet count (PLT) level.Results 2 a type of ALT and AST were significantly higher than those in patients with type 1 b patients (P < 0.05), and propagated, Hb, PLT, APQI level 1 b and 2 a type between the two there was no significant difference (P > 0.05).Conclusions HCV patients with type 2 a type 1 b severe degree of acute liver injury, but the severity of liver fibrosis type two no difference.
