医药前沿
醫藥前沿
의약전연
Yiayao Qianyan
2015年
26期
140-141
,共2页
急性ST段抬高心肌梗死%冠状动脉介入治疗%血栓抽吸导管%替罗非班
急性ST段抬高心肌梗死%冠狀動脈介入治療%血栓抽吸導管%替囉非班
급성ST단태고심기경사%관상동맥개입치료%혈전추흡도관%체라비반
Acute ST-segment elevation myocardial infarction%Percutaneous coronary intervention%Thrombus aspiration catheter%Tirofiban
目的:评价血栓抽吸导管联合替罗非班在急性S T段抬高心肌梗死(S T E M I)介入术中应用疗效.方法:选择2012年3月至2014年10月行急诊冠状动脉介入治疗(P C I)的急性S T段抬高心肌梗死患者86例,其中应用抽吸导管和替罗非班后行P C I组46例,常规P C I对照组40例.观察2组的造影结果、术后效果及安全性.结果:研究组发病距血管再通时间、术后2小时S T段回落>50%和心肌酶学峰值时间均优于对照组(均P<0.05);梗死相关血管(I R A)无复流发生率明显低于对照组(P<0.05),左室射血分数(LVEF)及左室舒张末内径(LVEDd)明显好于对照组,住院期间主要不良心血管事件(MACE,包括死亡、再梗死、再次靶血管重建)的发生率少于对照组,差异有统计学意义(P均<0.05).结论:血栓抽吸联合替罗非班治疗急性S T段抬高心肌梗死可减少无复流或慢血流发生,可改善术后心脏功能,并且不增加血管不良事件的发生率.
目的:評價血栓抽吸導管聯閤替囉非班在急性S T段抬高心肌梗死(S T E M I)介入術中應用療效.方法:選擇2012年3月至2014年10月行急診冠狀動脈介入治療(P C I)的急性S T段抬高心肌梗死患者86例,其中應用抽吸導管和替囉非班後行P C I組46例,常規P C I對照組40例.觀察2組的造影結果、術後效果及安全性.結果:研究組髮病距血管再通時間、術後2小時S T段迴落>50%和心肌酶學峰值時間均優于對照組(均P<0.05);梗死相關血管(I R A)無複流髮生率明顯低于對照組(P<0.05),左室射血分數(LVEF)及左室舒張末內徑(LVEDd)明顯好于對照組,住院期間主要不良心血管事件(MACE,包括死亡、再梗死、再次靶血管重建)的髮生率少于對照組,差異有統計學意義(P均<0.05).結論:血栓抽吸聯閤替囉非班治療急性S T段抬高心肌梗死可減少無複流或慢血流髮生,可改善術後心髒功能,併且不增加血管不良事件的髮生率.
목적:평개혈전추흡도관연합체라비반재급성S T단태고심기경사(S T E M I)개입술중응용료효.방법:선택2012년3월지2014년10월행급진관상동맥개입치료(P C I)적급성S T단태고심기경사환자86례,기중응용추흡도관화체라비반후행P C I조46례,상규P C I대조조40례.관찰2조적조영결과、술후효과급안전성.결과:연구조발병거혈관재통시간、술후2소시S T단회락>50%화심기매학봉치시간균우우대조조(균P<0.05);경사상관혈관(I R A)무복류발생솔명현저우대조조(P<0.05),좌실사혈분수(LVEF)급좌실서장말내경(LVEDd)명현호우대조조,주원기간주요불양심혈관사건(MACE,포괄사망、재경사、재차파혈관중건)적발생솔소우대조조,차이유통계학의의(P균<0.05).결론:혈전추흡연합체라비반치료급성S T단태고심기경사가감소무복류혹만혈류발생,가개선술후심장공능,병차불증가혈관불량사건적발생솔.
Objective To evaluate the effect of thrombus aspiration combined with Tirofiban During urgent percutaneous coronary intervention(PCI) in patients with acute myocardial infarction(AMI).Methods A total of 86 AMI patients with urgent PCI were enrolled from March 2012 to October 2014. There were 46 patients received PCI and suck by catheter combined with Tirofiban, another 40 patients received routine PCI. Observe the two groups of angiography, postoperatine efficacy, and safety.Results There was lower peak serum CK-MB, TNI in the study group, compared with the control group, ratio of ST segment resolution>50% and the coronary artery recanalization time was significantly better (P<0.05), no-refiow in Infarct-related Artery(IRA) after PCI was lower than the control group (P<0.05), left ventricular diastolic diameter(LVEDd), left ventricular ejection fraction(LVEF) and MACE rates in stady group were superior to those in the control group (P<0.05).Conclusion Application of suck by catheter combined with tirofiban in patients with acute myocardial infarction was effective, which could decrease no-reflow/slow flow and improve cardiac function after PCI. And dose not increase the incidence of blood vessel event.
