药品评价
藥品評價
약품평개
Drug Evaluation
2015年
20期
46-48
,共3页
大剂量%氨溴索%急性呼吸窘迫综合征%疗效%不良反应
大劑量%氨溴索%急性呼吸窘迫綜閤徵%療效%不良反應
대제량%안추색%급성호흡군박종합정%료효%불량반응
High dose%Ambroxol%Acute Respiratory Distress Syndrome%Efficacy%Adverse Reaction
本文通过临床药师对一例使用大剂量氨溴索治疗ARDS的案例进行疗效、不良反应的追踪及分析，并查阅国内外相关文献，得出大剂量氨溴索治疗ARDS的应用证据不足，特别是对其疗效是否呈剂量相关性、给药剂量、给药频次还缺乏大规模的实验研究。因此，临床上应谨慎使用。
本文通過臨床藥師對一例使用大劑量氨溴索治療ARDS的案例進行療效、不良反應的追蹤及分析，併查閱國內外相關文獻，得齣大劑量氨溴索治療ARDS的應用證據不足，特彆是對其療效是否呈劑量相關性、給藥劑量、給藥頻次還缺乏大規模的實驗研究。因此，臨床上應謹慎使用。
본문통과림상약사대일례사용대제량안추색치료ARDS적안례진행료효、불량반응적추종급분석，병사열국내외상관문헌，득출대제량안추색치료ARDS적응용증거불족，특별시대기료효시부정제량상관성、급약제량、급약빈차환결핍대규모적실험연구。인차，림상상응근신사용。
In this paper, the clinical pharmacist using large dose of ambroxol hydrochloride in the treatment of acute respiratory distress syndrome (ARDS)for 1 case, curative effect and adverse reaction of were tracked and analyzed, and concluded that there is insufficient evidence for the application of large dose of ambroxol in the treatment of ARDS, especially no evidence for the effect-dose relationship, dose and dosing frequency from a large-scale experimental study. Therefore, it should be cautious in clinical use.
