CAJ | 학술논문

目的：提高和完善平安丸的质量标准。方法：采用薄层色谱法对处方中母丁香、枳实进行了薄层色谱鉴别；采用高效液相色谱法对处方中木香的有效成分木香烃内酯、去氢木香烃内酯进行了含量测定。结果：薄层色谱斑点清晰、分离度好，阴性无干扰；木香烃内酯、去氢木香烃内酯进样量分别在0.1034-1.0335μg（r=0.9999），0.1101-1.1005μg（r=0.9997）范围内线性关系良好，平均回收率（n=6）分别为95.1%、98.6%，RSD分别为2.62%、2.84%。结论：本研究中的定性及定量方法简便准确、专属性强，能有效控制平安丸的质量。
목적：제고화완선평안환적질량표준。방법：채용박층색보법대처방중모정향、지실진행료박층색보감별；채용고효액상색보법대처방중목향적유효성분목향경내지、거경목향경내지진행료함량측정。결과：박층색보반점청석、분리도호，음성무간우；목향경내지、거경목향경내지진양량분별재0.1034-1.0335μg（r=0.9999），0.1101-1.1005μg（r=0.9997）범위내선성관계량호，평균회수솔（n=6）분별위95.1%、98.6%，RSD분별위2.62%、2.84%。결론：본연구중적정성급정량방법간편준학、전속성강，능유효공제평안환적질량。
This study was aimed to revise and improve the quality standard of Ping-An (PA) Pill. Fructus CaryophylliandFructus Aurantii ImmaturuswereidentifiedbyTLC.Thecontentofcostunolideand dehydrocostunolide were determined by HPLC. The results showed that there were clear spots, good degree of separation, and no negative interference in the TLC identification. The calibration curve of costunolide and dehydrocostunolide were linear at the range of 0.103 4-1.033 5μg (r=0.999 9) and 0.110 1-1.100 5μg (r=0.999 7). The average recoveries were 95.1% (RSD = 2.62%, n = 6) and 98.6% (RSD = 2.84%, n = 6), respectively. It was concluded that the method was convenient and accurate with strong specificity in the quality and quantity control of PA pill, which can be used in the quality control of PA pill.