世界中医药
世界中醫藥
세계중의약
World Chinese Medicine
2015年
10期
1509-1511,1514
,共4页
益气养阴%活血通络%糖尿病肾病
益氣養陰%活血通絡%糖尿病腎病
익기양음%활혈통락%당뇨병신병
Replenishing qi and nourishing yin%Activating blood and dredging collaterals%Diabetic nephropathy
目的：观察益气养阴、活血通络法对早期糖尿病肾病（Diabetic Nephropathy，DN）的临床疗效。方法：将符合标准的DN 患者58例，随机分为治疗组（29例）和对照组（29例），2组均予饮食控制、降糖等基础治疗，同时口服福辛普利10 mg，1次／d；治疗组在此基础上予以益气养阴、活血通络的中药，疗程为12周。对患者的尿微量白蛋白排泄率（UAER）、肾功能疗效、中医证候疗效、内生肌酐清除率（Ccr）等进行评价。结果：2组肾功能疗效比较，治疗组总有效率为82．76％，对照组总有效率为62．07％。中医证候疗效比较，治疗组总有效率为86．21％，对照组总有效率为58．62％。治疗组在降低患者的尿微量白蛋白排泄率和改善中医临床症状方面明显优于对照组（P ＜0．05）。整个试验过程中未出现任何不良反应及毒副作用。结论：益气养阴，活血通络法是防治早期糖尿病肾病的有效治法。
目的：觀察益氣養陰、活血通絡法對早期糖尿病腎病（Diabetic Nephropathy，DN）的臨床療效。方法：將符閤標準的DN 患者58例，隨機分為治療組（29例）和對照組（29例），2組均予飲食控製、降糖等基礎治療，同時口服福辛普利10 mg，1次／d；治療組在此基礎上予以益氣養陰、活血通絡的中藥，療程為12週。對患者的尿微量白蛋白排洩率（UAER）、腎功能療效、中醫證候療效、內生肌酐清除率（Ccr）等進行評價。結果：2組腎功能療效比較，治療組總有效率為82．76％，對照組總有效率為62．07％。中醫證候療效比較，治療組總有效率為86．21％，對照組總有效率為58．62％。治療組在降低患者的尿微量白蛋白排洩率和改善中醫臨床癥狀方麵明顯優于對照組（P ＜0．05）。整箇試驗過程中未齣現任何不良反應及毒副作用。結論：益氣養陰，活血通絡法是防治早期糖尿病腎病的有效治法。
목적：관찰익기양음、활혈통락법대조기당뇨병신병（Diabetic Nephropathy，DN）적림상료효。방법：장부합표준적DN 환자58례，수궤분위치료조（29례）화대조조（29례），2조균여음식공제、강당등기출치료，동시구복복신보리10 mg，1차／d；치료조재차기출상여이익기양음、활혈통락적중약，료정위12주。대환자적뇨미량백단백배설솔（UAER）、신공능료효、중의증후료효、내생기항청제솔（Ccr）등진행평개。결과：2조신공능료효비교，치료조총유효솔위82．76％，대조조총유효솔위62．07％。중의증후료효비교，치료조총유효솔위86．21％，대조조총유효솔위58．62％。치료조재강저환자적뇨미량백단백배설솔화개선중의림상증상방면명현우우대조조（P ＜0．05）。정개시험과정중미출현임하불량반응급독부작용。결론：익기양음，활혈통락법시방치조기당뇨병신병적유효치법。
Objective:To observe the therapeutic effects of replenishing qi and nourishing yin,activating blood and dredging col-laterals on the treatment of early diabetic nephropathy (DN).Methods:A total of 58 DN patients conforming to the diagnostic cri-teria were randomly divided into the treatment group (29 patients)and control group (29 patients).Besides the routine therapy including controlling diet,lowing blood glucose and orally taking fosinopril,10 mg daily,the treatment group was given Chinese medicine of replenishing qi and nourishing yin,activating blood and dredging collaterals for 12 weeks.The changes in UAER,cur-ative effect of renal function,TCMsyndrome score and Ccr were observed in the patients.Results:Curative effect of renal func-tion comparison,the total effective rate of the treatment group was 82.76% and that of control group was 62.07%.Syndromes curative effect comparison,the total effective rate of the treatment group was 86.21% and that of control group was 58.62%.The effect of treatment group was better than the control group in lowing UAER and improving Chinese medicine Syndromes,the differ-ence was significant(P <0.05).There were no obvious side effects found during the treatment.Conclusion:The method of re-plenishing qi and nourishing yin,activating blood and dredging collaterals showed better therapeutic efficacy in the treatment of early DN.
