CAJ | 학술논문

目的：观察归脾汤合柏子养心丸治疗心脾两虚型失眠的临床疗效。方法192例病例随机分为两组，每组96例。对照组给予阿普唑仑片，睡前口服。治疗组给予归脾汤加减合柏子养心丸治疗。2周为1个疗程，2个疗程后观察疗效。结果两组病例治疗后整体疗效比较差异有统计学意义，两组病例治疗后 SRSS 及 PSQI 评分均较本组治疗前明显降低，且治疗组降低更为明显，优于对照组治疗后。治疗组治疗后入睡时间、睡眠时间、夜间觉醒、困倦感、精力不足、多梦或噩梦均较治疗前明显改善，且优于对照组治疗后。结论归脾汤合柏子安神丸能够明显改善心脾两虚型失眠患者的睡眠质量及各项指标，且副反应明显减少，值得临床推广应用。
목적：관찰귀비탕합백자양심환치료심비량허형실면적림상료효。방법192례병례수궤분위량조，매조96례。대조조급여아보서륜편，수전구복。치료조급여귀비탕가감합백자양심환치료。2주위1개료정，2개료정후관찰료효。결과량조병례치료후정체료효비교차이유통계학의의，량조병례치료후 SRSS 급 PSQI 평분균교본조치료전명현강저，차치료조강저경위명현，우우대조조치료후。치료조치료후입수시간、수면시간、야간각성、곤권감、정력불족、다몽혹악몽균교치료전명현개선，차우우대조조치료후。결론귀비탕합백자안신환능구명현개선심비량허형실면환자적수면질량급각항지표，차부반응명현감소，치득림상추엄응용。
Objective To observe the clinical therapeutic effect of Guipi decoction combined with Boziyangxin pills in treating heart - spleen deficiency insomnia. Methods A total of 192 cases were random-ized to treatment group(n = 96)and control group(n = 96). Patients in the control group were given Alprazo-lam pillsbefore sleep. Patients in the treatment group received modified Guipi decoction and Boziyangxin pills. Two weeks were one treatment course,and therapeutic effect was observed after two treatment courses. Results There was statistically significant difference between the two groups in terms of the therapeutic effect after treatment. The SRSS and PSQI scores were obviously decreased in both groups,and the treatment group showed better outcomes. The time of falling asleep,sleep time,awake times during nights,exhaustion feeling,unenergetic condition,dreaminess,and nightmare all improved significantly in patients of treatment group. Conclusion Guipi decoction combined with Bozianshen pills can significant improve the sleep quality and the relevant index,and the side - effects are obviously decreased which is worth of application.