世界中西医结合杂志
世界中西醫結閤雜誌
세계중서의결합잡지
World Journal of Integrated Traditional and Western Medicine
2015年
10期
1412-1414
,共3页
慢性肾小球肾炎%槐杞黄颗粒剂%肝肾阴虚%临床研究
慢性腎小毬腎炎%槐杞黃顆粒劑%肝腎陰虛%臨床研究
만성신소구신염%괴기황과립제%간신음허%림상연구
Huaiqihuang particles%Chronic glomerulonephritis%Deficiency syndrome of both liver and kidney yin%Clinical observation
目的：探讨槐杞黄颗粒剂治疗慢性肾小球肾炎肝肾阴虚证中医证候的临床疗效。方法将符合纳入标准的受试患者随机分成槐杞黄颗粒剂高剂量组、低剂量组和对照组，分别以高剂量槐杞黄颗粒剂、低剂量槐杞黄颗粒剂、六味地黄汤治疗，两个月后观察疗效。结果①槐杞黄颗粒剂高剂量组、低剂量组和对照组均能明显改善患者中医证候，槐杞黄颗粒剂高剂量组与对照组中医证候临床痊愈率比较差异无统计学意义（P >0.05），但均明显优于槐杞黄颗粒剂低剂量组（P <0.05）。②槐杞黄颗粒剂高剂量组改善患者腰膝酸软、咽干舌燥证候明显优于对照组（P <0.05），对照组在改善患者潮热盗汗、五心烦热证候明显优于槐杞黄颗粒剂高剂量组（P <0.05），其他证候两组比较差异无统计学意义（P >0.05）。结论槐杞黄颗粒剂对改善慢性肾小球肾炎肝肾阴虚证有较好的疗效。
目的：探討槐杞黃顆粒劑治療慢性腎小毬腎炎肝腎陰虛證中醫證候的臨床療效。方法將符閤納入標準的受試患者隨機分成槐杞黃顆粒劑高劑量組、低劑量組和對照組，分彆以高劑量槐杞黃顆粒劑、低劑量槐杞黃顆粒劑、六味地黃湯治療，兩箇月後觀察療效。結果①槐杞黃顆粒劑高劑量組、低劑量組和對照組均能明顯改善患者中醫證候，槐杞黃顆粒劑高劑量組與對照組中醫證候臨床痊愈率比較差異無統計學意義（P >0.05），但均明顯優于槐杞黃顆粒劑低劑量組（P <0.05）。②槐杞黃顆粒劑高劑量組改善患者腰膝痠軟、嚥榦舌燥證候明顯優于對照組（P <0.05），對照組在改善患者潮熱盜汗、五心煩熱證候明顯優于槐杞黃顆粒劑高劑量組（P <0.05），其他證候兩組比較差異無統計學意義（P >0.05）。結論槐杞黃顆粒劑對改善慢性腎小毬腎炎肝腎陰虛證有較好的療效。
목적：탐토괴기황과립제치료만성신소구신염간신음허증중의증후적림상료효。방법장부합납입표준적수시환자수궤분성괴기황과립제고제량조、저제량조화대조조，분별이고제량괴기황과립제、저제량괴기황과립제、륙미지황탕치료，량개월후관찰료효。결과①괴기황과립제고제량조、저제량조화대조조균능명현개선환자중의증후，괴기황과립제고제량조여대조조중의증후림상전유솔비교차이무통계학의의（P >0.05），단균명현우우괴기황과립제저제량조（P <0.05）。②괴기황과립제고제량조개선환자요슬산연、인간설조증후명현우우대조조（P <0.05），대조조재개선환자조열도한、오심번열증후명현우우괴기황과립제고제량조（P <0.05），기타증후량조비교차이무통계학의의（P >0.05）。결론괴기황과립제대개선만성신소구신염간신음허증유교호적료효。
Objective To investigate the clinical efficacy of Huaiqihuang particles in treatment of deficiency syndrome of both liver and kidney yin in chronic glomerulonephritis. Methods The eligible sub-jects were randomly divided into high dose group,low dose group and control group. Therapeutic effect was observed after two months of treatment. Results The high dose group,low dose group and control group all significantly improved TCM syndromes,and the high dose group had no significant difference compared with the control group about effects of TCM syndrome(P > 0. 05),but it was significantly better than that of the low dose group(P < 0. 05). In addition,there were significant differences in terms of improving soreness -tired of waist,dry throat and tongue,the high dose group is better than the control group(P < 0. 05). Howev-er,the control group was better than the high dose group in terms of improving hectic fever and night swea-ting,dysphoria in chestpalms - soles(P < 0. 05). Conclusion Huaiqihuang particles has a good effect in improving the deficiency syndrome of both liver and kidney yin in chronic glomerulonephritis.
