CAJ | 학술논문

目的：分析和探讨肝硬化患者凝血功能检测的临床价值。方法选取广东省乐昌市中医院2013年1月—2014年1月收治的52例肝硬化患者（观察组），选取同时期在我院接受检查的52例健康人员（对照组），全部患者均进行凝血功能相关指标检查，包括纤维蛋白原（ FIB）、凝血酶时间（ TT）、血浆凝血酶原时间（ PT）、活化部分凝血活酶时间（ APTT）等指标，对检查结果进行分析。结果观察组患者纤维蛋白原水平明显低于对照组，凝血酶时间、活化部分凝血活酶时间及血浆凝血酶原时间较对照组显著延长，差异具有统计学意义（ P＜0.05）。结论血浆凝血因子异常是加重肝硬化发展的主要原因之一，对肝硬化患者凝血功能进行检测，有利于早期发现和辅助诊断疾病，对预防和治疗肝硬化出血具有重要的意义，值得临床推广应用。
목적：분석화탐토간경화환자응혈공능검측적림상개치。방법선취광동성악창시중의원2013년1월—2014년1월수치적52례간경화환자（관찰조），선취동시기재아원접수검사적52례건강인원（대조조），전부환자균진행응혈공능상관지표검사，포괄섬유단백원（ FIB）、응혈매시간（ TT）、혈장응혈매원시간（ PT）、활화부분응혈활매시간（ APTT）등지표，대검사결과진행분석。결과관찰조환자섬유단백원수평명현저우대조조，응혈매시간、활화부분응혈활매시간급혈장응혈매원시간교대조조현저연장，차이구유통계학의의（ P＜0.05）。결론혈장응혈인자이상시가중간경화발전적주요원인지일，대간경화환자응혈공능진행검측，유리우조기발현화보조진단질병，대예방화치료간경화출혈구유중요적의의，치득림상추엄응용。
Objective To analyze and probe into the clinical effects ofdetection of coagulation function in patients with liver cirrhosis.Methods 52 patients who suffered from the liver cirrhosis and who accepted treatments in our hospital from January, 2013 to January, 2014 were taken as the observation group, and selected in the same period 52 cases of healthy people who were accepted the inspection in our hospital as the control group.Then, all patients were coagulative function examination, including fibrinogen (FIB), thrombin time (TT), prothrombin time (PT), activation index of activated partial thromboplastin time ( APTT) , the examination results were compared.Results The fibrinogen levels of patients in the observation group were significantly lower than those of the control group, in addition, the thrombin time, activated partial thromboplastin time and prothrombin time were significantly longer than the control group, and the difference had statistically significant (P<0.05).Conclusion The plasma coagulation factor is one of the main reasons for the development of cirrhosis, which the detection of coagulation function in patients with liver cirrhosis is helpful for early detection and diagnosis of disease and it is of great significance for the prevention and treatment of liver cirrhosis,, thus should be promoted in the clinical application.