世界中医药
世界中醫藥
세계중의약
World Chinese Medicine
2015年
10期
1549-1551,1554
,共4页
多发性骨髓瘤%张镜人%中医%经验
多髮性骨髓瘤%張鏡人%中醫%經驗
다발성골수류%장경인%중의%경험
Multiple myeloma%Zhang Jingren%Traditional Chinese medicine%Experience
多发性骨髓瘤是一种浆细胞系恶性肿瘤，以骨髓中浆细胞恶性克隆增生，血清或尿液中出现单克隆免疫球蛋白或其成分（M蛋白），正常免疫蛋白受到抑制以及广泛溶骨病变和（或）骨质疏松为特征，引起骨折和骨髓功能衰竭，产生一系列临床症状，预后差[1]。张镜人老中医对多发性骨髓瘤的中医治疗有着深厚造诣，认为其病机乃肝肾气阴亏虚为本，外邪夹瘀痰阻络为标，治疗上扶正与祛邪并重，虚症以益气养阴、补益肝肾为主，实证以清热散瘀、凉血止血为主，有一定疗效。该文从中医病因、病机、治法、方药等角度对张教授治疗多发性骨髓瘤的临床心得进行探讨，并举验案1则。
多髮性骨髓瘤是一種漿細胞繫噁性腫瘤，以骨髓中漿細胞噁性剋隆增生，血清或尿液中齣現單剋隆免疫毬蛋白或其成分（M蛋白），正常免疫蛋白受到抑製以及廣汎溶骨病變和（或）骨質疏鬆為特徵，引起骨摺和骨髓功能衰竭，產生一繫列臨床癥狀，預後差[1]。張鏡人老中醫對多髮性骨髓瘤的中醫治療有著深厚造詣，認為其病機迺肝腎氣陰虧虛為本，外邪夾瘀痰阻絡為標，治療上扶正與祛邪併重，虛癥以益氣養陰、補益肝腎為主，實證以清熱散瘀、涼血止血為主，有一定療效。該文從中醫病因、病機、治法、方藥等角度對張教授治療多髮性骨髓瘤的臨床心得進行探討，併舉驗案1則。
다발성골수류시일충장세포계악성종류，이골수중장세포악성극륭증생，혈청혹뇨액중출현단극륭면역구단백혹기성분（M단백），정상면역단백수도억제이급엄범용골병변화（혹）골질소송위특정，인기골절화골수공능쇠갈，산생일계렬림상증상，예후차[1]。장경인로중의대다발성골수류적중의치료유착심후조예，인위기병궤내간신기음우허위본，외사협어담조락위표，치료상부정여거사병중，허증이익기양음、보익간신위주，실증이청열산어、량혈지혈위주，유일정료효。해문종중의병인、병궤、치법、방약등각도대장교수치료다발성골수류적림상심득진행탐토，병거험안1칙。
Multiple myeloma (MM)is a debilitating malignancy that is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance (MGUS)to plasma cell leukemia,which is featured by proliferation of malignant plasma cells and a subsequent overabundance of monoclonal paraprotein (M protein).It would cause fracture and bone function failure with a series of clinical symptoms with bad prognosis.The notable Chinese medicine doctor Profosser zhang Jingren has enriched experience and understanding on treating MM,who believes the disease mechanism is due the deficiency of liver-kidney yin,mani-fested with stasis and phlegm obstruction in channels.The treatment shall pay attention to both supporting right and dispelling evil. Benefiting qi and nourishing yin is applied to treat deficiency syndrome as well as tonifying liver and kidney.To treat excess syn-drome,clearing heat and dispelling stasis,cooling blood are applied.This paper explores the TCMcause,mechanism,rules,for-mula of MMfrom the clinical experience of professor Zhang Jingren.
