CAJ | 학술논문

目的：探讨自拟益气三仁汤对 IgA 肾病 Lee 分级Ⅰ、Ⅱ、Ⅲ，中医辨证为脾肾气虚湿热内蕴患者的影响及治疗效果。方法将62例患者分为中药组、激素组及中药加激素组，其中中药组，应用益气三仁汤治疗，不加激素；激素组应用激素治疗；中药加激素组采用益气三仁汤同时规律应用激素。观察两组病例治疗前后尿蛋白定量、血白蛋白、肝肾功能及中医证候评分等指标的变化。结果在尿蛋白定量及血白蛋白指标上激素组及中药加激素组在4周时均优于中药组，而在半年后中药组及中药加激素组均优于激素组。中医症状积分方面，中药组明显优于激素组及中药加激素组，而中药加激素组优于激素组。结论益气三仁汤对于 IgA 肾病治疗有效，值得临床推广应用。
목적：탐토자의익기삼인탕대 IgA 신병 Lee 분급Ⅰ、Ⅱ、Ⅲ，중의변증위비신기허습열내온환자적영향급치료효과。방법장62례환자분위중약조、격소조급중약가격소조，기중중약조，응용익기삼인탕치료，불가격소；격소조응용격소치료；중약가격소조채용익기삼인탕동시규률응용격소。관찰량조병례치료전후뇨단백정량、혈백단백、간신공능급중의증후평분등지표적변화。결과재뇨단백정량급혈백단백지표상격소조급중약가격소조재4주시균우우중약조，이재반년후중약조급중약가격소조균우우격소조。중의증상적분방면，중약조명현우우격소조급중약가격소조，이중약가격소조우우격소조。결론익기삼인탕대우 IgA 신병치료유효，치득림상추엄응용。
Objective To investigate the therapeutic effect of Yiqisanren decoction on IgA nephrop-athy Lee classification Ⅰ,Ⅱ,Ⅲ which the TCM syndrome differentiation is qi deficiency and damp - heat. Methods Sixty two patients were divided into Chinese medicine group,hormone group and hormone com-bined with Chinese medicine group. The Chinese medicine group applied Yiqisanren decoction without hor-mones. The hormone group gave patients a regular hormone therapy. The hormone combined with Chinese medicine group applied both Yiqisanren decoction and hormone. The urinary protein,serum albumin,liver function,renal function,and symptom scores of TCM were observed. Results The urinary protein and serum albumin in hormone group and hormone combined with Chinese medicine group were better than those of Chi-nese medicine group after 4 weeks,but after half a year the Chinese medicine group and hormone combined with Chinese medicine group were better and there was no significant differences between them. The symptom scores of TCM in Chinese medicine group and hormone combined with Chinese medicine group were better than those of hormone group. Conclusion Yiqisanren decoction is effective on the treatment of IgA nephropathy.