CAJ | 학술논문

目的：探讨替考拉宁不良反应发生原因和种类，为临床安全用药提供参考。方法：检索2000～2015年中国知网数据库、万方数据库、维普数据库等收载的国内期刊，进行回顾性分析和统计。结果：检索到有效病例19例，不良反应可发生在用药过程中和用药后各个时间段，且累及多个系统-器官，以过敏性反应（78.9%）居多，其次为泌尿系统损害（15.8%）、血液系统损害（10.5%）、神经系统损害（5.26%）。结论：临床医务人员应注意询问患者的过敏史，并结合患者的药敏结果使用该药；加强用药监测和药品不良反应监测。
목적：탐토체고랍저불량반응발생원인화충류，위림상안전용약제공삼고。방법：검색2000～2015년중국지망수거고、만방수거고、유보수거고등수재적국내기간，진행회고성분석화통계。결과：검색도유효병례19례，불량반응가발생재용약과정중화용약후각개시간단，차루급다개계통-기관，이과민성반응（78.9%）거다，기차위비뇨계통손해（15.8%）、혈액계통손해（10.5%）、신경계통손해（5.26%）。결론：림상의무인원응주의순문환자적과민사，병결합환자적약민결과사용해약；가강용약감측화약품불량반응감측。
Objective: To discuss the causes and type of the adverse drug reaction (ADR) cases induced by teicoplanin in order to provide references for clinical rational drug use. Method: Search CNKI, Wanfang Data, CQVIP for published reports on teicoplanin causing ADR during 2000 and 2015 and the statistical analysis was performed.Result:19 valid cases were retrieved. ADR could happen in the course of medication or anytime after medication. ADR could involve multiple systems and organs. Most of ADR were allergic reaction(78.9%), followed by urinary system damage(15.8%), hematological system damage(10.5%), and nervous system damage (5.26%). Conclusion: Clinicians should pay attention to the allergy history of patients, apply medication with the drug susceptibility results and strengthen the monitoring of adverse drug reactions and drug monitoring.