中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
30期
86-88
,共3页
高血压%美托洛尔%卡维地洛%血脂%血压%不良反应
高血壓%美託洛爾%卡維地洛%血脂%血壓%不良反應
고혈압%미탁락이%잡유지락%혈지%혈압%불량반응
Hypertension%Metoprolol%Carvedilol%Lipid%Blood pressure%Adverse reaction
目的：比较美托洛尔与卡维地洛治疗原发性高血压的效果。方法选取我院2013年8月~2014年8月收治的高血压患者110例，以随机数字表法将其分为两组，对照组予以美托洛尔治疗，观察组予以卡维地洛治疗，比较两组治疗效果及血压、血脂指标、不良反应。结果对照组治疗总有效率为70.91%，观察组治疗总有效率为92.73%，观察组治疗总有效率明显高于对照组(P<0.05)；与治疗前比较，两组治疗后舒张压、收缩压、总胆固醇、三酰甘油、低密度脂蛋白和高密度脂蛋白胆固醇均有改善，且观察组改善效果更为明显(P<0.05)；对照组出现2例不良反应，观察组出现3例不良反应，两组比较差异无统计学意义(P跃0.05)。结论与美托洛尔比较，卡维地洛对原发性高血压患者的治疗效果更佳，降压降脂效果更为显著，且用药安全可靠，值得推广。
目的：比較美託洛爾與卡維地洛治療原髮性高血壓的效果。方法選取我院2013年8月~2014年8月收治的高血壓患者110例，以隨機數字錶法將其分為兩組，對照組予以美託洛爾治療，觀察組予以卡維地洛治療，比較兩組治療效果及血壓、血脂指標、不良反應。結果對照組治療總有效率為70.91%，觀察組治療總有效率為92.73%，觀察組治療總有效率明顯高于對照組(P<0.05)；與治療前比較，兩組治療後舒張壓、收縮壓、總膽固醇、三酰甘油、低密度脂蛋白和高密度脂蛋白膽固醇均有改善，且觀察組改善效果更為明顯(P<0.05)；對照組齣現2例不良反應，觀察組齣現3例不良反應，兩組比較差異無統計學意義(P躍0.05)。結論與美託洛爾比較，卡維地洛對原髮性高血壓患者的治療效果更佳，降壓降脂效果更為顯著，且用藥安全可靠，值得推廣。
목적：비교미탁락이여잡유지락치료원발성고혈압적효과。방법선취아원2013년8월~2014년8월수치적고혈압환자110례，이수궤수자표법장기분위량조，대조조여이미탁락이치료，관찰조여이잡유지락치료，비교량조치료효과급혈압、혈지지표、불량반응。결과대조조치료총유효솔위70.91%，관찰조치료총유효솔위92.73%，관찰조치료총유효솔명현고우대조조(P<0.05)；여치료전비교，량조치료후서장압、수축압、총담고순、삼선감유、저밀도지단백화고밀도지단백담고순균유개선，차관찰조개선효과경위명현(P<0.05)；대조조출현2례불량반응，관찰조출현3례불량반응，량조비교차이무통계학의의(P약0.05)。결론여미탁락이비교，잡유지락대원발성고혈압환자적치료효과경가，강압강지효과경위현저，차용약안전가고，치득추엄。
Objective To compare the effects of metoprolol and carvedilol in treating primary hypertension. Methods From August 2013 to August 2014,110 patients with hypertension treated in our hospital were selected and divided into two groups by random number table.In the control group,metoprolol was provided,while in the observation group, carvedilol was used.The therapeutic effect,blood pressure,lipid levels,and adverse reaction between two groups were compared. Results In the control group,the total therapeutic effective rate was 70.91%,while the rate in the observation group was 92.73%,the rate in the observation group was higher than that in control group (P<0.05).In comparison with before treatment,the diastolic blood pressure,systolic blood pressure,total cholesterol,triglycerides,low density lipoprotein (LDL) and high density lipoprotein (HDL)after therapy was improved respectively,and the improvement in observation group was more obvious.Two cases occurred with adverse reactions in control group,while in observation group,there were 3 cases with adverse reactions,with no statistical differenc (P>0.05). Conclusion In comparison with metoprolol, carvedilol obtains a better therapeutic effect on treating primary hypertension as well as more remarkable effects on blood pressure and lipid lowering.It is safe and reliable in medication,and is worthy of promotion.
