CAJ | 학술논문

目的：观察5-氨基酮戊酸光动力（5-ALA-PDT）治疗面部多发性扁平疣的疗效和安全性。方法：将患者随机分为治疗组和对照组。治疗组：40例，用5-氨基酮戊酸光动力治疗，10～14d治疗1次，共治疗4次；对照组38例，外用5%咪喹莫特乳膏治疗，隔日治疗1次，连用8周。治疗结束后1个月观察疗效，末次治疗后连续随访3个月，以观察复发情况。结果：两组有效率比较差异有显著性（P＜0.05）；两组复发率比较无显著性差异（P＞0.05）。结论：5-氨基酮戊酸光动力（5-ALA-PDT）治疗面部多发性扁平疣是一种安全、有效，复发率低的治疗手段，值得临床推广。
목적：관찰5-안기동무산광동력（5-ALA-PDT）치료면부다발성편평우적료효화안전성。방법：장환자수궤분위치료조화대조조。치료조：40례，용5-안기동무산광동력치료，10～14d치료1차，공치료4차；대조조38례，외용5%미규막특유고치료，격일치료1차，련용8주。치료결속후1개월관찰료효，말차치료후련속수방3개월，이관찰복발정황。결과：량조유효솔비교차이유현저성（P＜0.05）；량조복발솔비교무현저성차이（P＞0.05）。결론：5-안기동무산광동력（5-ALA-PDT）치료면부다발성편평우시일충안전、유효，복발솔저적치료수단，치득림상추엄。
Objective To observe the efficacy of the ALA-PDT in treatment of generalized recalcitrant facial verruca plana. Methods The patients were randomly divided into two groups.40 cases of treatment group were treated by ALA-PDT every 10 to 14 days for four times in total,38 cases of control group treated by Imiquimod cream once every two days for eight weeks.All patients were followed up for 3 months. Results The effective rates of the treatment was higher than that of the control groups.There was a significant difference between the two groups(P<0.05).The recurrence rate of the treatment and the control groups were all 0,with no significant different(P>0.05). Conclusion ALA-PDT therapy is effective,safe for generalized recalcitrant facial verruca plana.