中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
Chinese Journal of Woman and Child Health Research
2015年
5期
1040-1041,1047
,共3页
新生儿疾病%甲状腺功能低下%可疑病人%检出率%采血时间
新生兒疾病%甲狀腺功能低下%可疑病人%檢齣率%採血時間
신생인질병%갑상선공능저하%가의병인%검출솔%채혈시간
neonatal disease%hypothyroidism%suspicious patients%detection rate%blood collection time
目的：对2012年1月至2014年6月北京市海淀区新生儿疾病筛查甲状腺功能低下的结果进行分析。方法采用回顾性研究的方法，对2012年1月至2014年6月海淀区新生儿疾病筛查甲状腺功能低下结果进行汇总，并与朝阳区及北京市筛查结果进行比较和分析。结果①先天性甲状腺功能低下（ CH）检出率为0．57‰，与朝阳区及北京市接近，差异无统计学意义（均P＞0．05）；②检出CH可疑病人1159人，检出率10．43‰，高于朝阳区及北京市，差异有统计学意义（χ2值分别为125．289、29．093，均P＜0．001）；③将全区各助产机构可疑病人检出率与朝阳进行比较，4家低于朝阳（甲组），14家高于朝阳（乙组），两组采血时间进行比较，甲组平均采血时间高于乙组，差异有统计学意义（t＝2．136，P＜0．05）。结论新生儿疾病筛查是早期发现先天性甲状腺功能低下的有效方法，可疑病人是发生甲状腺功能低下的高危人群。可疑病人需市、区及助产机构三级追访，可疑病人增多给各级人员增加工作量，给家庭和群众带来精神和经济负担，本文发现可疑病人检出率可能与采血时间有关，尚需进一步探讨。
目的：對2012年1月至2014年6月北京市海澱區新生兒疾病篩查甲狀腺功能低下的結果進行分析。方法採用迴顧性研究的方法，對2012年1月至2014年6月海澱區新生兒疾病篩查甲狀腺功能低下結果進行彙總，併與朝暘區及北京市篩查結果進行比較和分析。結果①先天性甲狀腺功能低下（ CH）檢齣率為0．57‰，與朝暘區及北京市接近，差異無統計學意義（均P＞0．05）；②檢齣CH可疑病人1159人，檢齣率10．43‰，高于朝暘區及北京市，差異有統計學意義（χ2值分彆為125．289、29．093，均P＜0．001）；③將全區各助產機構可疑病人檢齣率與朝暘進行比較，4傢低于朝暘（甲組），14傢高于朝暘（乙組），兩組採血時間進行比較，甲組平均採血時間高于乙組，差異有統計學意義（t＝2．136，P＜0．05）。結論新生兒疾病篩查是早期髮現先天性甲狀腺功能低下的有效方法，可疑病人是髮生甲狀腺功能低下的高危人群。可疑病人需市、區及助產機構三級追訪，可疑病人增多給各級人員增加工作量，給傢庭和群衆帶來精神和經濟負擔，本文髮現可疑病人檢齣率可能與採血時間有關，尚需進一步探討。
목적：대2012년1월지2014년6월북경시해정구신생인질병사사갑상선공능저하적결과진행분석。방법채용회고성연구적방법，대2012년1월지2014년6월해정구신생인질병사사갑상선공능저하결과진행회총，병여조양구급북경시사사결과진행비교화분석。결과①선천성갑상선공능저하（ CH）검출솔위0．57‰，여조양구급북경시접근，차이무통계학의의（균P＞0．05）；②검출CH가의병인1159인，검출솔10．43‰，고우조양구급북경시，차이유통계학의의（χ2치분별위125．289、29．093，균P＜0．001）；③장전구각조산궤구가의병인검출솔여조양진행비교，4가저우조양（갑조），14가고우조양（을조），량조채혈시간진행비교，갑조평균채혈시간고우을조，차이유통계학의의（t＝2．136，P＜0．05）。결론신생인질병사사시조기발현선천성갑상선공능저하적유효방법，가의병인시발생갑상선공능저하적고위인군。가의병인수시、구급조산궤구삼급추방，가의병인증다급각급인원증가공작량，급가정화군음대래정신화경제부담，본문발현가의병인검출솔가능여채혈시간유관，상수진일보탐토。
Objective To analyze the results of neonatal disease screening of congenital hypothyroidism ( CH) in Haidian District of Beijing from January 2012 to June 2014.Methods A retrospective study was carried out to summarize the screening results of CH in Haidian District from January 2012 to June 2014, and the results were compared with those in Chaoyang District and Beijing City.Results The detection rate of CH in Haidian District was 0.57‰, which was approximate to that in Chaoyang District and Beijing City.The difference among three areas was not significant (both P>0.05).There were 1 159 suspicious patients with CH in Haidian District, and the detection rate was 10.43‰, which was significantly higher than that in Chaoyang District and Beijing City (χ2 value was 125.289 and 29.093, respectively, both P<0.001).Compared with Chaoyang District, in Haidian District there were 4 midwifery institutions (group A) with lower detection rate of suspicious patients and 14 midwifery institutions ( group B) with higher detection rate.The average blood collection time of group A was longer than that of group B, and the difference was significant (t=2.136,P<0.05).Conclusion Neonatal disease screening is an effective method to detect CH early, and suspicious patients are the high risk population developing hypothyroidism. Suspicious patients require tertiary follow-up of municipal, district and midwifery institutions, and the increasing number of them increases burden on medical staff and mental and economic burden on family and society.The article shows that the detection rate of suspicious patients may be associated with blood collection time, which requires further exploration.
