中国实用医刊
中國實用醫刊
중국실용의간
Chinese Journal of Practical Medicine
2015年
23期
74-76
,共3页
胸腺肽%标准化疗%纵隔淋巴结核%临床效果
胸腺肽%標準化療%縱隔淋巴結覈%臨床效果
흉선태%표준화료%종격림파결핵%림상효과
Thymosin%Standard chemotherapy%Mediastinal lymphadenopathy%Clinical effect
目的 探讨纵隔淋巴结核采用胸腺肽与标准化疗方案联合治疗的临床效果. 方法 选取大同市第四人民医院2013年5月至2014年5月收治的80例纵隔淋巴结核患者,随机分为对照组和观察组各40例,分别进行标准化疗方案治疗与加用胸腺肽治疗,将其效果进行对比. 结果 观察组临床总有效率为100%,对照组为80%,差异有统计学意义(P<0.05). 观察组症状缓解时间为(20.1 ±7.9)d,明显短于对照组的(26.3 ±8.7)d,差异有统计学意义( P<0.05). 两组治疗1个月后均有1例肝功能出现异常,停用吡嗪酰胺,取复方甘草酸苷保肝治疗,观察肝功能恢复正常,抗结核治疗方案继续应用. 结论 在标准化疗方案应用的基础上,加强胸腺肽的应用,可显著提高纵隔淋巴结核治疗的临床效果,缩短病程,且有较高安全性,可显著提高患者的生存质量意义.
目的 探討縱隔淋巴結覈採用胸腺肽與標準化療方案聯閤治療的臨床效果. 方法 選取大同市第四人民醫院2013年5月至2014年5月收治的80例縱隔淋巴結覈患者,隨機分為對照組和觀察組各40例,分彆進行標準化療方案治療與加用胸腺肽治療,將其效果進行對比. 結果 觀察組臨床總有效率為100%,對照組為80%,差異有統計學意義(P<0.05). 觀察組癥狀緩解時間為(20.1 ±7.9)d,明顯短于對照組的(26.3 ±8.7)d,差異有統計學意義( P<0.05). 兩組治療1箇月後均有1例肝功能齣現異常,停用吡嗪酰胺,取複方甘草痠苷保肝治療,觀察肝功能恢複正常,抗結覈治療方案繼續應用. 結論 在標準化療方案應用的基礎上,加彊胸腺肽的應用,可顯著提高縱隔淋巴結覈治療的臨床效果,縮短病程,且有較高安全性,可顯著提高患者的生存質量意義.
목적 탐토종격림파결핵채용흉선태여표준화료방안연합치료적림상효과. 방법 선취대동시제사인민의원2013년5월지2014년5월수치적80례종격림파결핵환자,수궤분위대조조화관찰조각40례,분별진행표준화료방안치료여가용흉선태치료,장기효과진행대비. 결과 관찰조림상총유효솔위100%,대조조위80%,차이유통계학의의(P<0.05). 관찰조증상완해시간위(20.1 ±7.9)d,명현단우대조조적(26.3 ±8.7)d,차이유통계학의의( P<0.05). 량조치료1개월후균유1례간공능출현이상,정용필진선알,취복방감초산감보간치료,관찰간공능회복정상,항결핵치료방안계속응용. 결론 재표준화료방안응용적기출상,가강흉선태적응용,가현저제고종격림파결핵치료적림상효과,축단병정,차유교고안전성,가현저제고환자적생존질량의의.
Objective To investigate the clinical effect of thymosin combined with standard chemotherapy on me -diastinal lymphadenopathy .Methods Eighty cases of mediastinal lymphadenopathy in the fourth people ' s hospital of Da-tong from May 2013 to May 2014 were selected and divided into the control group and observation group , with 40 cases in each group . The control group received standard chemotherapy treatment and the observation group were given thymosin treatment in addition , and the effects were compared .Results The total effective rate ( 100%) in observation group was significantly higher than that of the control group (80%).The remission time [(20.1 ±7.9) d] in the observation group was significantly shorter than that of the control group[(26.3 ±8.7) d].After treatment, for one month, two cases with abnormal liver function occurred (one in each group ) , stopped using the pyrazinamide tablets and conducted the compound adenosine glycosides liver treatment , observed the hepatic function till it normal recoverd and continuing anti-TB treatment programs .Conclusions The appli-cation of thymosin combination therapy combined with standard chemotherapy can significantly improve the effect on medias -tinal lymphadenopathy , shorten the course , and enhance the quality of life of patients .
