CAJ | 학술논문

目的：探讨绝经后妇女子宫内膜息肉（ EP）发生恶变的相关危险因素。方法选取2010年6月至2013年6月间于临海市第一人民医院接受诊断和治疗的绝经后EP妇女246例，其中212例EP或者伴有单纯增生患者作为对照组，其余34例EP伴有非典型增生或者恶性癌变患者作为观察组。观察记录各种可能的相关因素，并进行单因素分析和回归分析。结果两组间年龄、绝经年限、糖尿病和高血压均属于绝经后妇女EP发生恶变可能的相关危险因素（ t值分别为8．334、7．623，χ2值分别为5．997、7．389，均P＜0．05）。通过进一步回归分析显示，年龄（＞60岁）与绝经年限（≥10年）为绝经后妇女EP发生恶变的危险因素（ OR值分别为7．824、11．137，均P＜0．05）。结论绝经后妇女EP发生恶变的相关危险因素主要是年龄和绝经年限，需要在临床中加以关注。
목적：탐토절경후부녀자궁내막식육（ EP）발생악변적상관위험인소。방법선취2010년6월지2013년6월간우림해시제일인민의원접수진단화치료적절경후EP부녀246례，기중212례EP혹자반유단순증생환자작위대조조，기여34례EP반유비전형증생혹자악성암변환자작위관찰조。관찰기록각충가능적상관인소，병진행단인소분석화회귀분석。결과량조간년령、절경년한、당뇨병화고혈압균속우절경후부녀EP발생악변가능적상관위험인소（ t치분별위8．334、7．623，χ2치분별위5．997、7．389，균P＜0．05）。통과진일보회귀분석현시，년령（＞60세）여절경년한（≥10년）위절경후부녀EP발생악변적위험인소（ OR치분별위7．824、11．137，균P＜0．05）。결론절경후부녀EP발생악변적상관위험인소주요시년령화절경년한，수요재림상중가이관주。
Objective To discuss the related risk factors of postmenopausal women with malignant endometrial polyps (EP).Methods Totally 246 patients with EP was selected during June 2010 to June 2013 in Linhai First People’ s Hospital of Zhejiang Province, and they were divided into control group (n=212) who had simple hyperplasia and observation group (n=34) who had malignant hyperplasia or atypical hyperplasia.All of possible factors were observed and they were analyzed by single factor analysis and regression analysis.Results Age, menopausal duration, diabetes and hypertension were the possible related risk factors of postmenopausal women with malignant EP ( t value was 8.334 and 7.623, respectively,χ2 value was 5.997 and 7.389, respectively, all P<0.05).Further regression analysis showed that age (>60 years) and menopausal duration (≥10 years) were the risk factors of postmenopausal women with malignant EP (OR value was 7.824 and 11.137, respectively, both P <0.05).Conclusion Age and menopausal duration are the related risk factors of postmenopausal women with malignant EP, which should attract attention in clinics.