临床与病理杂志
臨床與病理雜誌
림상여병리잡지
International Journal of Pathology and Clinical Medicine
2015年
10期
1783-1787
,共5页
姚碧容%成婧%钟昊%龚强
姚碧容%成婧%鐘昊%龔彊
요벽용%성청%종호%공강
维生素D%25-羟基维生素D%儿童%长沙
維生素D%25-羥基維生素D%兒童%長沙
유생소D%25-간기유생소D%인동%장사
vitamin D%25-hydroxyvitamin D%children%Changsha
目的:比较分析长沙地区部分儿童维生素D水平,为临床合理补充维生素D、改善儿童户外活动习惯以促进维生素D的合成提供科学依据。方法:收集我院2014年长沙地区16395例0~12岁健康体检儿童血清标本,通过酶联免疫吸附试验(ELISA)方法检测血清25-羟基维生素D[25-hydroxyvitamin D,25-(OH)D],采用单因素方差分析等统计学方法全面分析了不同年龄、性别以及一年中不同月份维生素D水平差异。结果:0~12岁儿童血清25-(OH)D平均水平为(59.2±24.5) nmol/L,远低于充足水平;<1月婴儿组与1~2月婴儿组间差异无统计学意义、学龄前组组与学龄组间差异无统计学意义(P>0.05),其他各组间差异均有统计学意义(P<0.05);不同性别间血清25-(OH)D水平差异无统计学意义(P>0.05);一年中10月份血清25-(OH)D水平最高,平均值为(68.5±24.8) nmol/L,1~10月水平呈逐步上升趋势,11月、12月又逐步下降。结论:长沙地区儿童需要增加户外活动时间,延长维生素D补充摄入时间,用以改善维生素D缺乏与不足的普遍现象。
目的:比較分析長沙地區部分兒童維生素D水平,為臨床閤理補充維生素D、改善兒童戶外活動習慣以促進維生素D的閤成提供科學依據。方法:收集我院2014年長沙地區16395例0~12歲健康體檢兒童血清標本,通過酶聯免疫吸附試驗(ELISA)方法檢測血清25-羥基維生素D[25-hydroxyvitamin D,25-(OH)D],採用單因素方差分析等統計學方法全麵分析瞭不同年齡、性彆以及一年中不同月份維生素D水平差異。結果:0~12歲兒童血清25-(OH)D平均水平為(59.2±24.5) nmol/L,遠低于充足水平;<1月嬰兒組與1~2月嬰兒組間差異無統計學意義、學齡前組組與學齡組間差異無統計學意義(P>0.05),其他各組間差異均有統計學意義(P<0.05);不同性彆間血清25-(OH)D水平差異無統計學意義(P>0.05);一年中10月份血清25-(OH)D水平最高,平均值為(68.5±24.8) nmol/L,1~10月水平呈逐步上升趨勢,11月、12月又逐步下降。結論:長沙地區兒童需要增加戶外活動時間,延長維生素D補充攝入時間,用以改善維生素D缺乏與不足的普遍現象。
목적:비교분석장사지구부분인동유생소D수평,위림상합리보충유생소D、개선인동호외활동습관이촉진유생소D적합성제공과학의거。방법:수집아원2014년장사지구16395례0~12세건강체검인동혈청표본,통과매련면역흡부시험(ELISA)방법검측혈청25-간기유생소D[25-hydroxyvitamin D,25-(OH)D],채용단인소방차분석등통계학방법전면분석료불동년령、성별이급일년중불동월빈유생소D수평차이。결과:0~12세인동혈청25-(OH)D평균수평위(59.2±24.5) nmol/L,원저우충족수평;<1월영인조여1~2월영인조간차이무통계학의의、학령전조조여학령조간차이무통계학의의(P>0.05),기타각조간차이균유통계학의의(P<0.05);불동성별간혈청25-(OH)D수평차이무통계학의의(P>0.05);일년중10월빈혈청25-(OH)D수평최고,평균치위(68.5±24.8) nmol/L,1~10월수평정축보상승추세,11월、12월우축보하강。결론:장사지구인동수요증가호외활동시간,연장유생소D보충섭입시간,용이개선유생소D결핍여불족적보편현상。
Objective: Analyzing the vitamin D level of children in Changsha area, to provide theoretical basis for clinical vitamin D supplement and improvement of vitamin D synthesis through outdoor activities.Methods: hTe serum samples of 0~12 years old healthy children of Changsha area in 2014 were collected. Serum 25-hydroxyvitamin D [25-(OH)D] concentrations were determined by ELISA kits. hTe differences of serum 25-(OH)D from different ages, gender, and months among a year were analyzed by One-Way ANOVA.Results: hTe average 25-(OH)D level of 0~12 years old healthy children was (59.2±24.5) nmol/L, far below the adequacy standards of >75 nmol/L. hTere was no statistical difference between <1 month old infant group and 1~2 months old infant group (P>0.05). There was no statistical difference between preschool age group and school age group (P>0.05). There was statistical difference between other groups (P<0.05). In 2014, the highest 25-(OH)D level appeared in October, was (68.5±24.8) nmol/L. hTe value of serum 25-(OH)D gradually increased from January to October, and then went down in November and December.Conclusion: Children in Changsha area needed to have more outdoor activities, and extend vitamin D supplement intake time, so that ameliorate the common phenomenon of vitamin D deifciency.