中国实用医药
中國實用醫藥
중국실용의약
China Practical Medical
2015年
32期
6-7,8
,共3页
慢性阻塞性肺疾病%肺动脉收缩压%活动耐力%六分钟步行试验
慢性阻塞性肺疾病%肺動脈收縮壓%活動耐力%六分鐘步行試驗
만성조새성폐질병%폐동맥수축압%활동내력%륙분종보행시험
Chronic obstructive pulmonary disease%Pulmonary arterial systolic pressure%Activity endurance%Six-minute walking test
目的:分析稳定期慢性阻塞性肺疾病(COPD)患者进行六分钟步行试验(6MWT)与动脉血气指标、肺通气功能指标、肺动脉收缩压(sPAP)的相关性,探讨影响COPD患者活动耐力的相关因素。方法60例COPD稳定患者根据六分钟步行距离(6MWD)分为A组(18例)、B组(21例)、C组(21例),分析肺通气功能参数、动脉血气参数、sPAP与6MWD的关系。结果三组一秒用力呼气容积(FEV1)和FEV1占预计值百分比(FEV1%pred)、氧分压(PaO2)、sPAP比较差异有统计学意义(P<0.05),进行多元逐步回归分析,其对6MWD影响的独立相关因素按其重要性依次为sPAP、FEV1、FEV1%pred。结论sPAP对COPD患者的活动耐力影响最大。6MWD可作为对COPD患者长期监测的一种手段,可对COPD患者病情的评价进行有效补充。
目的:分析穩定期慢性阻塞性肺疾病(COPD)患者進行六分鐘步行試驗(6MWT)與動脈血氣指標、肺通氣功能指標、肺動脈收縮壓(sPAP)的相關性,探討影響COPD患者活動耐力的相關因素。方法60例COPD穩定患者根據六分鐘步行距離(6MWD)分為A組(18例)、B組(21例)、C組(21例),分析肺通氣功能參數、動脈血氣參數、sPAP與6MWD的關繫。結果三組一秒用力呼氣容積(FEV1)和FEV1佔預計值百分比(FEV1%pred)、氧分壓(PaO2)、sPAP比較差異有統計學意義(P<0.05),進行多元逐步迴歸分析,其對6MWD影響的獨立相關因素按其重要性依次為sPAP、FEV1、FEV1%pred。結論sPAP對COPD患者的活動耐力影響最大。6MWD可作為對COPD患者長期鑑測的一種手段,可對COPD患者病情的評價進行有效補充。
목적:분석은정기만성조새성폐질병(COPD)환자진행륙분종보행시험(6MWT)여동맥혈기지표、폐통기공능지표、폐동맥수축압(sPAP)적상관성,탐토영향COPD환자활동내력적상관인소。방법60례COPD은정환자근거륙분종보행거리(6MWD)분위A조(18례)、B조(21례)、C조(21례),분석폐통기공능삼수、동맥혈기삼수、sPAP여6MWD적관계。결과삼조일초용력호기용적(FEV1)화FEV1점예계치백분비(FEV1%pred)、양분압(PaO2)、sPAP비교차이유통계학의의(P<0.05),진행다원축보회귀분석,기대6MWD영향적독립상관인소안기중요성의차위sPAP、FEV1、FEV1%pred。결론sPAP대COPD환자적활동내력영향최대。6MWD가작위대COPD환자장기감측적일충수단,가대COPD환자병정적평개진행유효보충。
Objective To analyze correlation between six-minute walking test (6MWT) and their arterial blood gas index, pulmonary ventilation function index, and pulmonary arterial systolic pressure (sPAP) in stable stage chronic obstructive pulmonary disease (COPD) patients, and to investigate related influencing factors of activity endurance in COPD patients.Methods A total of 60 stable stage COPD patients were divided by six-minute walking test distance (6MWD) into group A (18 cases), group B (21 cases) and group C (21 cases). Relationship of pulmonary ventilation function index, arterial blood gas index, sPAP, and 6MWD was analyzed.Results The difference of forced expiratory volume in one second (FEV1), FEV1 percentage predicted (FEV1%pred), arterial partial pressure of oxygen (PaO2), and sPAP had statistical significance in the three groups (P<0.05). Multiple stepwise regression analysis showed independent influencing factors of 6MWD were respectively sPAP, FEV1 and FEV1%pred. Conclusion sPAP has the largest influence on activity endurance in COPD patients. As a long-term monitoring measure for COPD patients, 6MWD can provide effective supplement to evaluation of COPD status in patients.