中国实用医药
中國實用醫藥
중국실용의약
China Practical Medical
2015年
32期
3-5
,共3页
冠状动脉疾病%血小板聚集抑制剂%血小板膜糖蛋白%D-二聚体
冠狀動脈疾病%血小闆聚集抑製劑%血小闆膜糖蛋白%D-二聚體
관상동맥질병%혈소판취집억제제%혈소판막당단백%D-이취체
Coronary artery disease%Platelet aggregation inhibitors%Platelet membrane glycoprotein%D-dimer
目的：探究冠心病患者血液中血小板膜糖蛋白(GP)和D-二聚体(D-D)的变化情况及临床意义。方法对37例不稳定型心绞痛(UA)患者(UA组),23例稳定型心绞痛(SA)患者(SA组)和30例正常人(对照组)体内的GP和D-D浓度进行检测,并对有无冠状动脉事件发生者之间的关系加以分析。结果UA组患者中GP和D-D浓度与SA组及对照组比较差异均有统计学意义(P<0.05)。有心血管事件发生组GP和D-D含量高于无心血管事件发生组,差异有统计学意义(P<0.05)。结论GP和D-D浓度能够当作冠状动脉血栓形成的重要指标,并可以在一定程度上将冠状动脉事件发生的危险性加以全面反映。
目的：探究冠心病患者血液中血小闆膜糖蛋白(GP)和D-二聚體(D-D)的變化情況及臨床意義。方法對37例不穩定型心絞痛(UA)患者(UA組),23例穩定型心絞痛(SA)患者(SA組)和30例正常人(對照組)體內的GP和D-D濃度進行檢測,併對有無冠狀動脈事件髮生者之間的關繫加以分析。結果UA組患者中GP和D-D濃度與SA組及對照組比較差異均有統計學意義(P<0.05)。有心血管事件髮生組GP和D-D含量高于無心血管事件髮生組,差異有統計學意義(P<0.05)。結論GP和D-D濃度能夠噹作冠狀動脈血栓形成的重要指標,併可以在一定程度上將冠狀動脈事件髮生的危險性加以全麵反映。
목적：탐구관심병환자혈액중혈소판막당단백(GP)화D-이취체(D-D)적변화정황급림상의의。방법대37례불은정형심교통(UA)환자(UA조),23례은정형심교통(SA)환자(SA조)화30례정상인(대조조)체내적GP화D-D농도진행검측,병대유무관상동맥사건발생자지간적관계가이분석。결과UA조환자중GP화D-D농도여SA조급대조조비교차이균유통계학의의(P<0.05)。유심혈관사건발생조GP화D-D함량고우무심혈관사건발생조,차이유통계학의의(P<0.05)。결론GP화D-D농도능구당작관상동맥혈전형성적중요지표,병가이재일정정도상장관상동맥사건발생적위험성가이전면반영。
ObjectiveTo investigate changes and clinical significance of platelet membrane glycoprotein (GP) and D-dimer (D-D) in coronary heart disease patients.MethodsGP and D-D in 37 unstable angina (UA) patients (UA group), 23 stable angina (SA) patients (SA group) and 30 normal people (control group) were detected. Relationship between patients with and without coronary artery incident was analyzed.ResultsThere were statistically significant differences of GP and D-D between UA group and SA group, control group (P<0.05). The cardiovascular event group had higher GP and D-D levels than non-cardiovascular event group, and the difference had statistical significance (P<0.05).Conclusion Concentration of GP and D-D can be taken as important indexes for coronary arterial thrombosis, and they can fully reveal risk of coronary artery incident to a certain degree.
