CAJ | 학술논문

目的：检测肝硬化患者血清生化和血细胞学指标，探讨异常结果在治疗、监测方面与疾病转归的关系。方法全自动生化分析仪检测生化项目，全自动血球分析仪检测血细胞学项目，全自动血凝仪检测血浆凝血酶原时间和凝血酶原活动度，对患者临床体征及症状进行咨询统计。结果与对照组比较，肝硬化患者血清酶活性、总胆汁酸、直接胆红素、凝血酶原时间、白蛋白、球蛋白和白细胞、血红蛋白、红细胞、血小板总数结果异常，差异显著（P＜0．05或P＜0．01），肝硬化患者固有的临床体征和症状表现突出。结论肝硬化患者血清生化和细胞学项目检测结果异常，反映了患者病情严重，是该病终末期的结局，且患者特有的体征和并发症出现是肝功能衰竭的标志。异常结果检出率越多，预后则不良。
목적：검측간경화환자혈청생화화혈세포학지표，탐토이상결과재치료、감측방면여질병전귀적관계。방법전자동생화분석의검측생화항목，전자동혈구분석의검측혈세포학항목，전자동혈응의검측혈장응혈매원시간화응혈매원활동도，대환자림상체정급증상진행자순통계。결과여대조조비교，간경화환자혈청매활성、총담즙산、직접담홍소、응혈매원시간、백단백、구단백화백세포、혈홍단백、홍세포、혈소판총수결과이상，차이현저（P＜0．05혹P＜0．01），간경화환자고유적림상체정화증상표현돌출。결론간경화환자혈청생화화세포학항목검측결과이상，반영료환자병정엄중，시해병종말기적결국，차환자특유적체정화병발증출현시간공능쇠갈적표지。이상결과검출솔월다，예후칙불량。
Objective To investigate the relationship between abnormal results and prognosis of the liver cirrhosis in treatment and monitoring .Methods Full automatic biochemical analyzer were used to measure the biochemical ge-nomics project ,full automatic blood cell analyzer were employed to detect the hemocytology project ,while full automat-ic blood coagulation analyzer were made to detect the original time and activity of plasma prothrombin , and clinical signs and symptoms of the patients were compared .Results Compared with the control group ,the activity of plasma prothrombin,total bile acid,direct bilirubin,prothrombin time serum albumin,globulin and white blood cell, hemoglobin ,red blood cell ,platelet count in patients with liver cirrhosis were abnormal .The difference was significant (P<0.05 or P<0.01).The inherent clinical signs and symptoms of patients with liver cirrhosis were obvious .Con-clusion The abnormal results of serum biochemistry and hemocytology in liver cirrhosis indicate that the patients are in critical condition .And the appearance of patients'specific signs and complications marks the hepatic failure .The more the abnormal results ,the worse the prognosis .