中国实用医药
中國實用醫藥
중국실용의약
China Practical Medical
2015年
33期
6-7,8
,共3页
肝动脉栓塞%原发性肝癌%肝功能
肝動脈栓塞%原髮性肝癌%肝功能
간동맥전새%원발성간암%간공능
Transcatheter arterial chemoembolization%Primary liver cancer%Liver function
目的：研究肝动脉栓塞(TACE)治疗原发性肝癌对肝功能的影响，并分析肝损害与碘化油含量的关系。方法128例原发性肝癌患者给予 TACE 术治疗，采集术前1 d 和术后1周空腹静脉血，分析肝功能变化与碘化油之间的关系。结果术前与术后谷丙转氨酶(ALT)比较差异有统计学意义(P<0.05)，术前与术后谷氨酰转肽酶(GGT)、碱性磷酸酶(ALP)及肝功能分级情况比较差异无统计学意义(P>0.05)。碘化油用量<10 ml 与11~15 ml 及16~20 ml 与>20 ml 的肝损害加重率比较，差异无统计学意义(P>0.05)；碘化油用量>15 ml 与≤15 ml 的肝损害加重率比较差异有统计学意义(P<0.05)。结论 TACE 术治疗肝恶性肿瘤对肝功能有一定损伤，且在行 TACE 术治疗肝癌时要注意碘化油用量，要重视术前术后肝功能损害。
目的：研究肝動脈栓塞(TACE)治療原髮性肝癌對肝功能的影響，併分析肝損害與碘化油含量的關繫。方法128例原髮性肝癌患者給予 TACE 術治療，採集術前1 d 和術後1週空腹靜脈血，分析肝功能變化與碘化油之間的關繫。結果術前與術後穀丙轉氨酶(ALT)比較差異有統計學意義(P<0.05)，術前與術後穀氨酰轉肽酶(GGT)、堿性燐痠酶(ALP)及肝功能分級情況比較差異無統計學意義(P>0.05)。碘化油用量<10 ml 與11~15 ml 及16~20 ml 與>20 ml 的肝損害加重率比較，差異無統計學意義(P>0.05)；碘化油用量>15 ml 與≤15 ml 的肝損害加重率比較差異有統計學意義(P<0.05)。結論 TACE 術治療肝噁性腫瘤對肝功能有一定損傷，且在行 TACE 術治療肝癌時要註意碘化油用量，要重視術前術後肝功能損害。
목적：연구간동맥전새(TACE)치료원발성간암대간공능적영향，병분석간손해여전화유함량적관계。방법128례원발성간암환자급여 TACE 술치료，채집술전1 d 화술후1주공복정맥혈，분석간공능변화여전화유지간적관계。결과술전여술후곡병전안매(ALT)비교차이유통계학의의(P<0.05)，술전여술후곡안선전태매(GGT)、감성린산매(ALP)급간공능분급정황비교차이무통계학의의(P>0.05)。전화유용량<10 ml 여11~15 ml 급16~20 ml 여>20 ml 적간손해가중솔비교，차이무통계학의의(P>0.05)；전화유용량>15 ml 여≤15 ml 적간손해가중솔비교차이유통계학의의(P<0.05)。결론 TACE 술치료간악성종류대간공능유일정손상，차재행 TACE 술치료간암시요주의전화유용량，요중시술전술후간공능손해。
Objective To research influence by transcatheter arterial chemoembolization (TACE) on liver function in the treatment of primary liver cancer, and to analyze relationship between hepatic lesion and content of iodinated oil. Methods There were 128 patients with primary liver cancer receiving TACE for treatment. Their fasting venous blood in 1 d before operation and 1 week after operation were taken for analysis of relationship between liver function and iodinated oil. Results The difference of alanine aminotransferase (ALT) before and after operation had statistical significance (P<0.05). The differences of gamma-glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), and liver function classification before and after operation had no statistical significance (P>0.05). Exacerbation rate of hepatic lesion by contents of iodinated oil as <10 ml and 11~15 ml had no statistically significant difference with those as 16~20 ml and >20 ml (P>0.05). Contents of iodinated oil as >15 ml and ≤ 15 ml had statistically significant difference in exacerbation rate of hepatic lesion (P<0.05). Conclusion TACE will provide certain damage to liver function in treating primary liver cancer, and it is essential to pay attention to content of iodinated oil during TACE, preoperative and postoperative liver function damage.
