CAJ | 학술논문

目的：了解妊娠期妇女在不同孕期血清铁蛋白(SF)、叶酸(FA)和25羟基维生素 D (25OHD)检测的意义。方法运用化学发光免疫分析法检测150例作产前保健的孕妇(妊娠组)、55例无贫血症状健康妊娠妇女(对照2组)在不同孕期及55例健康体检合格的非妊娠妇女(对照1组)的 SF、FA和25OHD 含量。结果随着孕期的增加三项的含量都逐渐下降，与对照组相比，妊娠组早孕的 SF、25OHD 较低，差异具有统计学意义(P<0.05)， FA 比较差异无统计学意义(P>0.05)，中、晚期的 SF、FA 和25OHD 含量均比对照组低，差异具有统计学意义(P<0.01)。随着孕期的增加， SF 和 FA 低下检出率逐渐升高，差异具有统计学意义(P<0.05)。结论检测妊娠期妇女在不同孕期 SF、FA 和25OHD 含量可以对妊娠期贫血的防治提供帮助，保障母婴安全。
목적：료해임신기부녀재불동잉기혈청철단백(SF)、협산(FA)화25간기유생소 D (25OHD)검측적의의。방법운용화학발광면역분석법검측150례작산전보건적잉부(임신조)、55례무빈혈증상건강임신부녀(대조2조)재불동잉기급55례건강체검합격적비임신부녀(대조1조)적 SF、FA화25OHD 함량。결과수착잉기적증가삼항적함량도축점하강，여대조조상비，임신조조잉적 SF、25OHD 교저，차이구유통계학의의(P<0.05)， FA 비교차이무통계학의의(P>0.05)，중、만기적 SF、FA 화25OHD 함량균비대조조저，차이구유통계학의의(P<0.01)。수착잉기적증가， SF 화 FA 저하검출솔축점승고，차이구유통계학의의(P<0.05)。결론검측임신기부녀재불동잉기 SF、FA 화25OHD 함량가이대임신기빈혈적방치제공방조，보장모영안전。
Objective To understand significance of serum ferritin (SF), folic acid (FA) and 25-hydroxyitamin D (25OHD) detection in pregnant women during different duration. Methods Chemiluminescence immunoassay was applied to detect SF, FA, and 25OHD contents in 150 pregnant women receiving prenatal care (pregnancy group), 55 healthy pregnant women without anemia (control group 2), and 55 healthy non-pregnant women (control group 1). Results Contents of the three indexes decreased along with progress of pregnancy. Comparing with the control groups, the pregnancy group had lower SF and 25OHD in early pregnancy, and their difference had statistical significance (P<0.05). Their difference of FA had no statistical significance (P>0.05). Moderate and late pregnancy had all lower SF, FA and 25OHD than the control groups, and their difference had statistical significance (P<0.01). Detection rate of SF and FA deficiency increased gradually along with progress of pregnancy, and the difference had statistical significance (P<0.05). Conclusion Detection of SF, FA, and 25OHD in pregnant women during different duration is helpful to prevent anemia during pregnancy and guarantee maternal and neonatal safety.