CAJ | 학술논문

目的探讨血液灌流序贯高容量血液滤过对感染性休克患者降钙素原水平的影响.方法 37例感染性休克患者, 随机分为对照组(18例)和治疗组(19例).对照组给予常规抗感染等综合治疗, 治疗组在常规综合治疗基础上, 应用血液灌流序贯高容量血液滤过治疗, 测定两组患者入住ICU及治疗72 h后血清降钙素原水平.结果两组入住ICU时血清降钙素原比较, 差异无统计学意义(P>0.05);治疗72 h后血清降钙素原组间相比差异具有统计学意义(P<0.05).结论血液灌流序贯高容量血液滤过可以下调感染性休克患者降钙素原的表达, 对感染性休克的治疗有益.
목적 탐토혈액관류서관고용량혈액려과대감염성휴극환자강개소원수평적영향.방법 37례감염성휴극환자, 수궤분위대조조(18례)화치료조(19례).대조조급여상규항감염등종합치료, 치료조재상규종합치료기출상, 응용혈액관류서관고용량혈액려과치료, 측정량조환자입주ICU급치료72 h후혈청강개소원수평.결과 량조입주ICU시혈청강개소원비교, 차이무통계학의의(P>0.05);치료72 h후혈청강개소원조간상비차이구유통계학의의(P<0.05).결론 혈액관류서관고용량혈액려과가이하조감염성휴극환자강개소원적표체, 대감염성휴극적치료유익.
To investigate influence of hemoperfusion sequential high volume hemofiltration on procalcitonin level in septic shock patients.Methods A total of 37 septic shock patients were randomly divided into control group (18 cases) and treatment group (19 cases). The control group received comprehensive treatment by conventional anti-infection, and the treatment group received additional hemoperfusion sequential high volume hemofiltration for treatment. Procalcitonin levels in the two groups were detected in ICU admission and 72 h after treatment.Results There was no statistically significant difference of serum procalcitonin between the two groups in ICU admission (P>0.05), while the difference after 72 h of treatment had statistical significance between the two groups (P<0.05).Conclusion Hemoperfusion sequential high volume hemofiltration can reduce expression of procalcitonin in septic shock patients, and it is beneficial for septic shock treatment.