CAJ | 학술논문

目的：探讨抗血小板药物对冠心病患者介入术后无复流发生率的影响。方法选取180例冠心病行冠状动脉血管介入治疗的并且发生无复流现象的患者作为研究对象，将其随机分成观察组与对照组各90例。其中观察组介入术后产生无复流或慢复流时给予盐酸替罗非班治疗，对照组给予维拉帕米治疗。结果观察组注射药物末次冠脉造影显示TIMI 3级例数多于对照组，差异具有统计学意义（ p＜0.05）；用药后首次和末次冠状动脉造影观察组TMPG3级率明显高于对照组，差异具有统计学意义（p＜0.05）。结论与维拉帕米相比，盐酸替罗非班能有效减少冠心病患者介入术后无复流发生率，适合在临床上推广使用。
목적：탐토항혈소판약물대관심병환자개입술후무복류발생솔적영향。방법선취180례관심병행관상동맥혈관개입치료적병차발생무복류현상적환자작위연구대상，장기수궤분성관찰조여대조조각90례。기중관찰조개입술후산생무복류혹만복류시급여염산체라비반치료，대조조급여유랍파미치료。결과관찰조주사약물말차관맥조영현시TIMI 3급례수다우대조조，차이구유통계학의의（ p＜0.05）；용약후수차화말차관상동맥조영관찰조TMPG3급솔명현고우대조조，차이구유통계학의의（p＜0.05）。결론여유랍파미상비，염산체라비반능유효감소관심병환자개입술후무복류발생솔，괄합재림상상추엄사용。
Objective To investigate the influence of antiplatelet drugs in patients with coronary heart dis-ease after intervention incidence of no -reflow.Methods 180 cases of coronary artery interventional treatment of coronary heart disease and patients with no -reflow phenomenon as research subjects were randomly divided into ob-servation group and the control group of 90 cases.Observation group after intervention produce given tirofiban hydro-chloride treatment of no -reflow or slow reflow, and the control group received verapamil therapy .Results The final group was injected with drugs Coronary angiography showed TIMI 3 cases number than the control group , and the difference was statistically significant ( p<0.05);After treatment of coronary angiography for the first time , the last observation group was significantly higher level TMPG3, and the difference was statistically significant (p<0.05). Conclusion Compared with verapamil hydrochloride tirofiban in patients with coronary heart disease , intervention can effectively reduce postoperative incidence of no -reflow, which should be spreaded in clinical practice .