国际药学研究杂志
國際藥學研究雜誌
국제약학연구잡지
Journal of International Pharmaceutical Research
2015年
5期
650-653
,共4页
王银%李跃辉%蔡萍%彭宇%张水寒
王銀%李躍輝%蔡萍%彭宇%張水寒
왕은%리약휘%채평%팽우%장수한
二至丸%正交实验%成型工艺
二至汍%正交實驗%成型工藝
이지환%정교실험%성형공예
Erzhi pill%orthogonal test%molding process
目的 优化二至丸的成型工艺. 方法 以二至丸外观性状、丸重差异和溶散时限的综合评分为考察指标,采用L9(34)正交实验法对二至丸的成型工艺中清膏相对密度(A)、药粉细度(B)、药粉与中蜜比例(C)3个因素进行优化研究. 结果 优选出二至丸的最佳成型工艺为:清膏相对密度为1.25,药粉细度为100目,药粉与中蜜比例为1:0.6. 结论 优选出的成型工艺经验证重复性良好,简单可行,所制的二至丸外观圆整、色泽均匀、溶散时限短,为二至丸的成型工艺研究提供了依据.
目的 優化二至汍的成型工藝. 方法 以二至汍外觀性狀、汍重差異和溶散時限的綜閤評分為攷察指標,採用L9(34)正交實驗法對二至汍的成型工藝中清膏相對密度(A)、藥粉細度(B)、藥粉與中蜜比例(C)3箇因素進行優化研究. 結果 優選齣二至汍的最佳成型工藝為:清膏相對密度為1.25,藥粉細度為100目,藥粉與中蜜比例為1:0.6. 結論 優選齣的成型工藝經驗證重複性良好,簡單可行,所製的二至汍外觀圓整、色澤均勻、溶散時限短,為二至汍的成型工藝研究提供瞭依據.
목적 우화이지환적성형공예. 방법 이이지환외관성상、환중차이화용산시한적종합평분위고찰지표,채용L9(34)정교실험법대이지환적성형공예중청고상대밀도(A)、약분세도(B)、약분여중밀비례(C)3개인소진행우화연구. 결과 우선출이지환적최가성형공예위:청고상대밀도위1.25,약분세도위100목,약분여중밀비례위1:0.6. 결론 우선출적성형공예경험증중복성량호,간단가행,소제적이지환외관원정、색택균균、용산시한단,위이지환적성형공예연구제공료의거.
Objective To optimize the molding process of Erzhi pill. Methods Using the external properties of pill, the pill weight, disintegration time as the comprehensive evaluation index, the L9(34) orthogonal test was used to test the effects of three factors:the relative density of thick paste(A), the powder fineness(B), and the proportion of powder and honey(C). Results The best molding process was as follows: the relative density of thick paste was 1.25, the powder fineness was 100 meshes, and the proportion of powder and honey was 1: 0.6. Conclusion This optimized molding process proved to be repeatable, simple and feasible. The Erzhi pill made by this preparation technology are round, the color and luster are uniform and the dissolving time is short. It provides the basis for studying the molding process of Erzhi pill .